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All times are CEST (UTC + 2)
| West Ham – Manchester City | 0:5 (end) | | | Bournemouth – Sheffield Utd. | 1:1 (end) | | | Burnley – Southampton | 3:0 (end) |
| Crystal Palace – Everton | 0:0 (end) | | | Tottenham – Aston Villa | 3:1 (end) |
| Groningen – Twente | 1:3 (end) | | | Ajax – Emmen | 5:0 (end) | | | Willem II – Arnhem | 0:2 (end) |
| Oostende – Club Brugge | 0:2 (end) | | | Eupen – Waasland-Beveren | 1:1 (end) | | | Genk – Waregem | 0:2 (end) |
| Santa Clara – Famalicão | 0:2 (end) | | | SL Benfica – FC Ferreira | 5:0 (end) |
| Admira – Linz | 0:1 (end) | | | Rapid – Rheindorf Altach | 2:1 (end) | | | Salzburg – Wolfsberger | 5:2 (end) |
| Orenburg – Tambov | 2:2 (end) | | | Dynamo – FC Zenit | 0:2 (end) | | | FK Krasnodar – Kazaň | 1:0 (end) |
| Ostrava – Bohemians 1905 | 4:2 (end) | | | Olomouc – Karviná | 1:1 (end) | | | Příbram – Č. Budějovice | 2:0 (end) |
| Slavia – Liberec | 1:0 (end) |
| Ružomberok – Žilina | 2:3 (end) | | | Michalovce – Senica | 3:0 (end) | | | Trenčín – Dunajská Streda | 2:1 (end) |
| Slovan Bratislava – Zlaté Moravce | 4:0 (end) | | | Nitra – Sereď | 3:2 (end) |
| Verl – Augsburg | 2:1 (end) | | | Würzburger – Hoffenheim | 3:3 (4:5 after SO) | | | Atlas Delmenhorst – Bremen | 1:6 (end) |
| Atlético – Juventus | 2:1 (end) |
final
Burnley FC
3:0
(0:0)
Southampton FC
Goals:
63. A. Barnes (Pieters), 70. A. Barnes (Pieters), 75. Gudmundsson
Ball possession: 46 % : 54 %.
Shots on target: 4:3. Shots off target: 4:5. Corners: 2:7. Offsides: 5:1. Fouls: 6:12.
Referees: Scott – Davies, Garratt
Attendance: 19784
Penalty missed:
Ball possession: 46 % : 54 %.
Shots on target: 4:3. Shots off target: 4:5. Corners: 2:7. Offsides: 5:1. Fouls: 6:12.
Burnley FC:
Pope – Lowton, Tarkowski, Mee (C), Pieters – Gudmundsson, Cork, A. Westwood, McNeil (84. Lennon) – Wood, A. Barnes (84. Jay Rodriguez).
Subs: Hart – Bardsley, B. Gibson, Lennon, Hendrick, Jay Rodriguez, K. Long.
Coach:
Southampton FC: Gunn – Bednarek, J. Stephens (73. P.-E. Höjbjerg), Vestergaard – Valery, Ward-Prowse (C), Romeu, Bertrand – Adams (73. Boufal), Redmond – Ings (66. Obafemi).
Subs: A. McCarthy – Boufal, Djenepo, P.-E. Höjbjerg, Soares, Obafemi, Jošida.
Coach:
Subs: Hart – Bardsley, B. Gibson, Lennon, Hendrick, Jay Rodriguez, K. Long.
Coach:
Southampton FC: Gunn – Bednarek, J. Stephens (73. P.-E. Höjbjerg), Vestergaard – Valery, Ward-Prowse (C), Romeu, Bertrand – Adams (73. Boufal), Redmond – Ings (66. Obafemi).
Subs: A. McCarthy – Boufal, Djenepo, P.-E. Höjbjerg, Soares, Obafemi, Jošida.
Coach:
Referees: Scott – Davies, Garratt
Attendance: 19784
Burnley FC substitution: Dwight McNeil is replaced by Aaron Lennon.
Southampton FC substitution: Jack Stephens is replaced by Pierre-Emile Höjbjerg.