Penalty missed:

BV De Graafschap: Jurjus – Will, Straalman, R. Pröpper, Tesselaar – Smeets, Diemers, Driver – Koolhof (72. Peters) – Vermeij, Parzyszek (59. Kabasele).
Subs: Verstappen – Bouma, Kaak, Peters, Çiçek, K. Vida, Kabasele.
Coach:

Go Ahead Eagles: Zwarthoed – Lambooij, Vriends, Schenk, van der Meer – Nieveld, Teijsse, Duits – van Overbeek (63. Maatsen), de Kogel (83. Groenbast), Wolters.
Subs: Cummins – van Ewijk, Maatsen, ten Den, Džepar, Daemen, Groenbast.
Coach:

Referees: Blom – Geutjes, Langkamp

Attendance:

Penalty missed:

FC Utrecht: Bednarek – Troupee (85. Rubin), van der Maarel, W. Janssen (C), Leeuwin, S. Amrabat – Strieder (71. Boymans), Barazite, Ludwig – Haller, Joosten.
Subs: Nijhuis – Boymans, Letschert, Rubin, Ligeon, Ulusoy, D. Rosheuvel.
Coach:

Heracles Almelo: B. Castro – Droste, te Wierik, Zomer, Gosens – Bruns (C) (77. van Ooijen), Pelupessy, Bel Hassani – Navrátil (90+2. Fledderus), Weghorst, Darri (63. Gladon).
Subs: Fij – Breukers, Bosz, Gladon, van Ooijen, Fledderus, Hoogma.
Coach:

Referees: Kuipers

Attendance:

Penalty missed:

Willem II Tilburg: Lamprou – Heerkens, Wuytens, Peters (C), Achenteh (82. Joppen) – Haemhouts (79. Braber), Kali, Ojo – Hupperts (90+1. van der Velden), Falkenburg, Andersen
Subs: Koppers, Ondaan, Bruno Andrade, Braber, Meul, van der Velden, Joppen
Coach:

NAC Breda: ten Rouwelaar – Stam, Pedro (70. Naah), van der Weg, Gorter – Suk (89. Robinson), Duarte (60. Brands), Seuntjens, Matič – Ünal, Ars (C)
Subs: Mulder, Lazić, Brands, Naah, Noppert, Dingsdag, Robinson
Coach:

Referees: Makkelie – Diks, Steegstra

Attendance:

Penalty missed:

Club Bruggy KV: Butelle – Meunier (54. De fauw), Mechele, Denswil, de Bock – Claudemir, Vormer (80. Vossen), Simons (C) – Vanaken, Diaby, Izquierdo (48. Dierckx)
Subs: Wesley, Vossen, Bruzzese, Coopman, Dierckx, Bolingoli Mbombo, De fauw
Coach:

KV Oostende: Biebauw – Vandendriessche, Rozehnal, Milić, Antunes – Jali, Berrier (64. Jonckheere), Siani (C) – Musona, Akpala (54. Cyriac), El Ghanassy (77. Godwin)
Subs: Ovono, de Schutter, Cyriac, Pedersen, Jonckheere, Godwin, Godeau
Coach:

Referees:

Attendance:

Penalty missed:

KAA Gent: Sels – Nielsen, Gershon, Asare – Foket, Kums "C", Neto – Miličević (78. Boussoufa), Saief, Simon (90+2. Schoofs) – Depoitre.
Subs: Thoelen – Rafinha, Boussoufa, Diedhiou, Mitrović, Schoofs, Van der Bruggen, Deaux, Wikheim.
Coach:

KRC Genk: Bizot – Walsh (84. Kumordzi), Dewaest, Kabasele, Uronen – Pozuelo, Ndidi – Kebano (63. Karelis) – Buffel "C", Bailey – Samatta (63. de Camargo).
Subs: Köteles – Hamalainen, Karelis, Kumordzi, de Camargo, Wouters, Buyens.
Coach:

Referees: B. Vertenten – R. Vanyzere, N. Ponsar

Attendance:

Penalty missed:

RSC Anderlecht: Proto (K) – De Medina, Kara, Nuytinck, Büttner – Tielmans, Praet – Suráez (77. Sylla), Duričič (77. Ezekiel), Acheampong – Okaka (62. Lukebakio).
Subs: Roef – Conte, Nsakala, Heylen, Sylla, Lukebakio, Ezekiel Trenér: Hasi.
Coach:

SV Zulte-Waregem: Bossut – Dalsgaard, Baudry, Diallo, Verboom (78. Buyl) – Meite, Lepoint – Cordaro, Kaya, Bentek – Leye (K).
Subs: Steppe – Sami, Poletanovič, Buyl, Storm, Zauda, De Smet. Trenér: Dury.
Coach:

Referees: Dierick – Walschap, Divincenzo

Attendance: 19 500