Penalty missed:

Chelsea FC: Courtois – Ivanović (C), Cahill, Luiz, Azpilicueta – Kanté – Willian (83. Moses), Oscar (84. Pedro), Matić (84. Fàbregas), E. Hazard – D. Costa.
Subs: Begović – Alonso, Aina, Fàbregas, Moses, Pedro, Batshuayi.
Coach:

Liverpool FC: Mignolet – Clyne, Matip, Lovren – Milner, Lallana, Хендерсон (C), Coutinho, Wijnaldum (90. Stewart) – Mané, Sturridge (57. Origi).
Subs: Karius – A. Moreno, Stewart, Lucas Leiva, Grujić, Ejaria, Origi.
Coach:

Referees: Martin Atkinson – Stephen Child, Stuart Burt

Attendance: 41 514

Penalty missed: 79. Ponce (GRN), keeper Adán saved

Real Betis: Adán – Piccini, Mandi, Pezzella, Durmisi – Petros, Ruiz (36. Musonda), Brašanac (86. Gutiérrez) – Joaquín (75. Zozulja), Alegría, Rubén Castro.
Subs: D. Giménez – Bruno González, Gutiérrez, Cejudo, Zozulja, Musonda, D. Ceballos.
Coach:

Granada CF: Ochoa – Foulquier, Vezo, G. Silva, Tabanou (46. Tito) – Krhin, Pereira – Carcela-González, Bueno (56. Angban), Atzili (86. Kravec) – Ponce.
Subs: Olazábal – Tito, J. Márquez, Boga, Cuenca, Kravec, Angban.
Coach:

Referees: De Cerro – Yuste, Álvarez

Attendance: 36 090

Penalty missed:

1. FC Kolín nad Rýnem: Horn – F. Sørensen, Mavraj, Heintz, Hector – Risse, Lehmann (C), Höger, Bittencourt (50. Zoller) – Osako (65. Olkowski), Modeste (81. Jojić).
Subs: Müller – Olkowski, S. Özcan, Jojić, Mladenović, Klünter, Zoller.
Coach:

SC Freiburg: Schwolow – Günter, Gulde (77. Niedermeier), Söyüncü (46. Petersen), Stenzel – Grifo – Höfler, Frantz (C), Bulut (65. Haberer) – Niederlechner, Philipp.
Subs: Gikiewicz – Niedermeier, Ignjovski, Meffert, Abrashi, Haberer, Petersen.
Coach:

Referees:

Attendance:

Penalty missed:

FC Utrecht: Ruiter – Troupee, Leeuwin (75. W. Janssen), Koch, van der Meer (66. Moore) – S. Amrabat, Strieder, Joosten (58. Barazite) – Ayoub – Haller (C), R. Živković.
Subs: Jensen – W. Janssen, Barazite, Ludwig, Rubin, Kerk, de Lange, Moore.
Coach:

FC Groningen: Padt (C) – Davidson, K. Larsen, Memišević, Hateboer – Hiariej, Jenssen (84. Reijnen), Linssen (75. van Weert) – Mahi (82. Rusnák), Hoesen, Idrissi.
Subs: van der Lei, van der Vlag – Reijnen, Rusnák, Bacuna, van Weert, Sørloth, van der Laan, van Nieff, Maduro, Tibbling.
Coach:

Referees: D. Higler – C. Dobre, R. Brondijk (E. Blank)

Attendance:

Penalty missed:

Sporting Charleroi: Penneteau – Mata, Martos, Willems, N'Ganga – Fall, Marcq, Diandy (84. Ninis), Baby – Pollet (46. Bedia), Bakar (62. Benavente).
Subs: Boulenger, Benavente, Hendrickx, Dessoleil, Ninis, Mandanda, Bedia
Coach:

YR KV Mechelen: Moris – Paulussen, De Witte, Cocalić – Croizet (72. Veselinović), Rizz, El Messaoudi, Bjelica – Schouterden, Verdier (64. Kolovos), Matthys (88. Cobbaut).
Subs: Veselinović, Kolovos, Cobbaut, Coosemans, Van Cleemput, Callebaut, Claes
Coach:

Referees: Dierick – Dens, Lesceux

Attendance: 7592

Penalty missed:

CD Nacional: Silva – Agra, Correia, Figueiredo, Garcia, Hamzaoui (83. Bonilla), Rorrigues (57. Wyllian), Sequeira, Jota, Washington, Witi (70. Campos)
Subs: Bonilla, Willyan, Campos, Geraldo, Hugo, Roniel, Bolat
Coach:

CS Marítimo: Gottardi – Cléber (46. Ghazaryan), Costa (78. Diawara), China, Fransergio, Mauricio, Santos, Sen, Silva, Sousa, Xavier (57. Baldé)
Subs: Dirceu, Patrick, Diawara, Baldé, Ghazaryan, Charles, Éber
Coach:

Referees:

Attendance:

Penalty missed:

FK Orenburg: Abakumov – Malych, Oyewole, Andrejev, Polujachtov – Afonin – Něchajčik, Vorobjev (72. Bamba), Georgiev, Jefremov (86. Koronov) – Prudnikov (67. Sanaja).
Subs: Ruděnko, Gutor – Bamba, Žunić, Šogenov, Poměrko, Sanaja, Koronov, Vasijev, Batov, Děľkin, Kacapalov.
Coach:

FK Spartak Moskva: Rebrov – Ješčenko (87. Kutin), Kutěpov, Bocchetti, D. Kombarov – Promes, Rômulo, Fernando, Zobnin (90. Zujev) – Ananidze (81. I. Popov) – Luís.
Subs: Pesjakov – Zujev, Maurício, Melkadze, Tasci, Pucko, Kutin, I. Popov, Davydov.
Coach:

Referees:

Attendance: