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All times are CEST (UTC + 2)
| Arsenal – Aston Villa | 4:0 (end) | | | Southampton – Crystal Palace | 4:1 (end) | | | Chelsea – Leicester | 1:1 (end) |
| West Brom – Liverpool | 1:1 (end) | | | Swansea – Manchester City | 1:1 (end) | | | Everton – Norwich | 3:0 (end) |
| Watford – Sunderland | 2:2 (end) | | | Newcastle – Tottenham | 5:1 (end) | | | Stoke – West Ham | 2:1 (end) |
| Malaga – Las Palmas | 4:1 (end) | | | Espanyol – Eibar | 4:2 (end) | | | Gijón – Villarreal | 2:0 (end) |
| Betis – Getafe | 2:1 (end) | | | Rayo Vallecano – Levante | 3:1 (end) |
| Heracles – Groningen | 5:1 (after OT) | | | Utrecht – Zwolle | 5:2 (end) |
| Club Bruggy – Anderlecht | 4:0 (end) | | | Waregem – Gent | 4:2 (end) |
| Moreirense – Marítimo | 2:1 (end) | | | SL Benfica – Nacional | 4:1 (end) | | | Braga – Sporting | 0:4 (end) |
| Salzburg – Wolfsberger | 1:0 (end) | | | Rheindorf Altach – Ried | 0:0 (end) | | | Austria – Sturm Graz | 3:0 (end) |
| Admira – Rapid | 1:3 (end) | | | Mattersburg – Grödig | 2:3 (end) |
| Samara – Kazaň | 1:1 (end) | | | Machačkala – Saransk | 3:0 (end) | | | FC Zenit – Lok. Moskva | 1:1 (end) |
final
Arsenal FC
4:0
(1:0)
Aston Villa FC
Goals:
5. Giroud (Monreal), 78. Giroud (Özil), 80. Giroud (Bellerín), 90+3. Bunn (own)
Ball possession: 60 % : 40 %.
Shots on target: 7:3. Shots off target: 7:0. Corners: 5:4. Offsides: 0:0. Fouls: 12:6.
Referees: M. Clattenburg – J. Brooks, A. Halliday (R. East)
Attendance:
Cards: 39. C. Sánchez (ASV)
Penalty missed:
Ball possession: 60 % : 40 %.
Shots on target: 7:3. Shots off target: 7:0. Corners: 5:4. Offsides: 0:0. Fouls: 12:6.
Arsenal FC:
Čech – Bellerín, Gabriel, Koscielny (C), Monreal – Coquelin, Wilshere (69. Elneny) – Cazorla (88. Campbell), Özil (88. Arteta), Alexis Sánchez – Giroud.
Subs: Ospina – Gibbs, Arteta, Elneny, Ramsey, Iwobi, Campbell.
Coach:
Aston Villa FC: Bunn – Lyden (75. Grealish), Lescott (C) (65. Richards), Toner, Cissokho – C. Sánchez, A. Westwood, Gueye – Bacuna, J. Ayew, Sinclair.
Subs: Guzan – Richards, Traoré, Gil, Hepburn-Murphy, Grealish, Gestede.
Coach:
Subs: Ospina – Gibbs, Arteta, Elneny, Ramsey, Iwobi, Campbell.
Coach:
Aston Villa FC: Bunn – Lyden (75. Grealish), Lescott (C) (65. Richards), Toner, Cissokho – C. Sánchez, A. Westwood, Gueye – Bacuna, J. Ayew, Sinclair.
Subs: Guzan – Richards, Traoré, Gil, Hepburn-Murphy, Grealish, Gestede.
Coach:
Referees: M. Clattenburg – J. Brooks, A. Halliday (R. East)
Attendance:
Arsenal FC substitution: Mesut Özil is replaced by Mikel Arteta.