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All times are CEST (UTC + 2)
| Stoke – Leicester | 2:2 (end) | | | Huddersfield Town – West Brom | 1:0 (end) | | | Newcastle – Bournemouth | 0:1 (end) |
| Southampton – Burnley | 0:1 (end) | | | West Ham – Liverpool | 1:4 (end) |
| Valencia – Leganés | 3:0 (end) | | | La Coruňa – Atlético | 0:1 (end) | | | Alavés – Espanyol | 1:0 (end) |
| Barcelona – Sevilla | 2:1 (end) |
| RB Leipzig – Hannover | 2:1 (end) | | | Freiburg – Schalke | 0:1 (end) | | | Mönchengladbach – Mohuč | 1:1 (end) |
| Augsburg – Leverkusen | 1:1 (end) | | | Hamburg – Stuttgart | 3:1 (end) | | | Dortmund – Bayern | 1:3 (end) |
| Alkmaar – Willem II | 3:2 (end) | | | Excelsior – Kerkrade | 1:0 (end) | | | Heracles – Groningen | 2:1 (end) |
| Venlo – Breda | 0:0 (end) |
| Genk – Lokeren | 0:0 (end) | | | Mechelen – Kortrijk | 2:0 (end) | | | Sint-Truiden – Eupen | 4:4 (end) |
| Waasland-Beveren – Mouscron | 2:0 (end) |
| Moreirense – Portimonense | 1:1 (end) | | | Tondela – Boavista | 3:2 (end) | | | Estoril – Rio Ave | 0:2 (end) |
| Porto – Belenenses | 2:0 (end) |
| Sturm Graz – Rapid | 0:0 (end) | | | Rheindorf Altach – Linec | 2:4 (end) | | | Admira – Wolfsberger | 0:0 (end) |
| Tosno – FK Krasnodar | 1:3 (end) | | | Grozny – Rostov | 1:0 (end) |
| Dukla Praha – Karviná | 3:2 (end) | | | Teplice – Slovácko | 3:0 (end) | | | Ostrava – Mladá Boleslav | 0:1 (end) |
| Jihlava – Liberec | 3:1 (end) | | | Bohemians 1905 – Olomouc | 1:1 (end) |
final
SC Freiburg
0:1
(0:0)
Schalke 04
Goals:
62. D. Caligiuri (Burgstaller)
Ball possession: 51 % : 49 %.
Shots on target: 2:3. Shots off target: 9:5. Corners: 6:1. Offsides: 0:0. Fouls: 14:12.
Referees: Brych – Borsch, Lupp
Attendance: 24000
Cards: 87. Kath (FRE) – 88. Stambouli (SCH)
Penalty missed:
Ball possession: 51 % : 49 %.
Shots on target: 2:3. Shots off target: 9:5. Corners: 6:1. Offsides: 0:0. Fouls: 14:12.
SC Freiburg:
Schwolow – Koch, Schuster (C), Stanko Stanko – Stenzel, Höfler, Frantz (61. Abraši), Günter – Haberer, Petersen (78. Terrazzino), Kapustka (75. Kath).
Subs: Gikiewicz – Abraši, Kath, Kempf, Kübler, Ravet, Terrazzino.
Coach:
Schalke 04: Fährmann (C) – Stambouli, Naldo, Kehrer – D. Caligiuri, McKennie, Meyer, Oczipka – Di Santo (79. Embolo), Burgstaller (90+3. Reese), Konopljanka (65. Harit).
Subs: Nübel – Coke, Bentaleb, Embolo, Harit, Reese, Schöpf.
Coach:
Subs: Gikiewicz – Abraši, Kath, Kempf, Kübler, Ravet, Terrazzino.
Coach:
Schalke 04: Fährmann (C) – Stambouli, Naldo, Kehrer – D. Caligiuri, McKennie, Meyer, Oczipka – Di Santo (79. Embolo), Burgstaller (90+3. Reese), Konopljanka (65. Harit).
Subs: Nübel – Coke, Bentaleb, Embolo, Harit, Reese, Schöpf.
Coach:
Referees: Brych – Borsch, Lupp
Attendance: 24000
Scorer is DANIEL CALIGIURI. Assisted by Guido Burgstaller.