Penalty missed:

Sporting Gijón: Cuéllar – O. Vranješ, L. Hernández, Meré, Isma López – Aït-Atmane, S. Álvarez (C) – Carmona (82. Menéndez), Ndi (9. Halilović), Jony – Guerrero (70. C. Castro).
Subs: Alberto García – Barrera, Menéndez, Lora, Halilović, C. Castro, Mascarell.
Coach:

Rayo Vallecano: Carlos – Quini (16. Iturra), Tito, Dorado, N. Martínez – D. Llorente, Trashorras (C) – P. Hernández (81. Piti), Jo. Sánchez, Bébé (71. Embarba) – Fedor.
Subs: Y. Rodríguez – Manucho, Embarba, Piti, Caballero, Iturra, Crespo.
Coach:

Referees: Clos Gómez – Javier Aguilar, Luis Marco

Attendance:

Penalty missed:

1. FSV Mohuč 05: Karius – Donati, Balogun, Bell, Bussmann – Baumgartlinger, Latza – Clemens, Malli (87. Frei), Jairo (83. De Blasis) – Córdoba (90+4. Bungert).
Subs: Curci – Bengtsson, Brosinski, Moritz, Frei, Bungert, De Blasis.
Coach:

Schalke 04: Fährmann – Caiçara (66. Riether), Matip, Neustädter, Kolašinac – Geis, Goretzka – Sané (84. Di Santo), Meyer, Belhanda – Huntelaar.
Subs: Gspurning – Friedrich, Di Santo, Sam, Højbjerg, Schöpf, Riether.
Coach:

Referees: Grafe – Kleve, Sinn

Attendance:

Penalty missed:

SC Cambuur Leeuwarden: Nienhuis (C) – Peersman, Dammers, Lachman, Andriuškevičius (82. Houtkoop) – J. Byrne, Hiariej (83. Hoefdraad), Monteiro – Barto (40. Vloet), van de Streek, van Veen.
Subs: Zeinstra – Overgoor, Houtkoop, M. Rosheuvel, Hoefdraad, Vloet, van der Laan.
Coach:

FC Utrecht: Ruiter – van der Maarel (C), Leeuwin, Letschert, Ligeon – Ramselaar, Strieder, Ayoub (39. Ludwig) – Haller, Barazite, Joosten (66. Boymans).
Subs: Bednarek – Boymans, Ludwig, S. Amrabat, Kallon, Abena, Troupee.
Coach:

Referees: Nijhuis – van de Ven, Schaap

Attendance:

Penalty missed:

KAA Gent: Sels – Nielsen, Mitrović, Asare – Foket, Deaux (68. Milicevic), Kums (C), Matton (81. Coulibaly), Dejaegere – Depoitre, Simon (27. Boussoufa)
Subs: Rafinha, Boussoufa, Coulibaly, Renato Neto, Vandenbussche, Diedhiou, Saief, Milicevic
Coach:

Royal Excel Mouscron: Vagner – Oussalah (78. Mézague), Dusenne (C), Aksentijević, Vaccaro, Castelletto – Peyre, Hubert, Michel (60. Mohamed) – Badri, Marković (67. Viola)
Subs: Mézague, Mohamed, Rausin, Viola, Amallah, Maciel, Olinga
Coach:

Referees: Lambrechts – De Rocker, Plumes

Attendance:

Penalty missed:

SL Benfica: César – Almeida, Nilsson-Lindelöf, Jardel, Eliseu – Gaitan, Samaris, Sanches, Pizzi – Miitroglou, Jonas
Subs: Moraes – Jiménez, Salvio, Sílvio, Talisca, Carcela, Semedo
Coach:

FC Porto: Casillas – M. Pereira, Awaziem, Indi, Layún – Herrera, D. Pereira, Andre – Corona, Aboubakar, Brahimi
Subs: Helton – Rúben Neves, Varela, Marega, Oliveira, Ángel, Suk
Coach:

Referees: Estádio da Luz

Attendance:

Penalty missed:

FK Dukla Praha: Hroššo – Milošević, Gorkšs, Štetina, Vrzal – Marek Hanousek (C), Považanec, Albiach – Berger (85. Manzia), Vašíček (87. Smejkal), Breznaník (68. Mareš).
Subs: David Tetour – Daniel Tetour, Kovaľ, Manzia, Mareš, Preisler, Smejkal.
Coach:

FC Slovan Liberec: Koubek – Hovorka, Bartošák, Pokorný (C), Ljulka (63. Bartl) – Karafiát, Sýkora, Folprecht (80. Shala), Jefremov (46. Vůch) – Bakoš, Rabušic.
Subs: Hladký – Luckassen, Breite, Bartl, Machuča, Vůch, Shala.
Coach:

Referees: Zelinka – Pelikán, Paták

Attendance: