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| Tottenham – Manchester City | 4:1 (end) | | | Leicester – Arsenal | 2:5 (end) | | | Liverpool – Aston Villa | 3:2 (end) |
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| Heerenveen – Arnhem | 0:0 (end) | | | Utrecht – Cambuur | 3:3 (end) | | | Ajax – Groningen | 2:0 (end) |
| Alkmaar – Heracles | 3:1 (end) | | | Eindhoven – Nijmegen | 2:1 (end) |
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| Standard – Leuven | 2:2 (end) |
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| Austria – Wolfsberger | 1:0 (end) |
| CSKA Moskva – Lok. Moskva | 1:1 (end) | | | Machačkala – Ufa | 1:1 (end) | | | Spartak – FC Zenit | 2:2 (end) |
| Olomouc – Zlín | 1:1 (end) | | | Dukla Praha – Brno | 1:2 (end) | | | Příbram – Jihlava | 4:1 (end) |
| Slovácko – Bohemians 1905 | 1:0 (end) | | | Teplice – Ostrava | 1:0 (end) | | | Plzeň – Liberec | 2:1 (end) |
| Senica – Myjava | 0:1 (end) | | | Trenčín – Skalica | 3:0 (end) | | | Ružomberok – Dunajská Streda | 1:0 (end) |
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83
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AZ Alkmaar substitution: Dabney dos Santos Souza is replaced by Thom Haye.
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72
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Heracles Almelo substitution: Thomas Bruns is replaced by Peter van Ooijen.
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64
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AZ Alkmaar substitution: Vincent Janssen is replaced by Robert Mühren.
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55
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AZ Alkmaar substitution: Rajko Brezančić is replaced by Ridgeciano Haps.
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28
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Heracles Almelo substitution: Brahim Darri is replaced by Robin Gosens.
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27
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Heracles Almelo substitution: Mark-Jan Fledderus is replaced by Jaroslav Navrátil.
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Goals:
15. Henriksen, 17. Gouweleeuw, 81. Tanković – 76. Navrátil
Ball possession: 47 % : 53 %.
Shots on target: 11:2. Shots off target: 10:9. Corners: 8:10. Offsides: 2:2. Fouls: 12:10.
Referees:
Attendance:
Cards: 54. M. Johansson (ALK), 68. Gouweleeuw (ALK), 82. Tanković (ALK) – 19. Zomer (HRC)
Penalty missed:
Ball possession: 47 % : 53 %.
Shots on target: 11:2. Shots off target: 10:9. Corners: 8:10. Offsides: 2:2. Fouls: 12:10.
AZ Alkmaar:
Coutinho – M. Johansson, Gouweleeuw, van der Linden, Brezančić (55. Haps) – van Overeem, Henriksen, B. Rienstra – Tanković, V. Janssen (64. Mühren), Souza (83. T. Haye).
Subs: Olij – J. Wuytens, Hupperts, T. Haye, Mühren, Luckassen, Haps.
Coach:
Heracles Almelo: B. Castro – Droste, te Wierik, Zomer, Fledderus (27. Navrátil) – Bruns (72. van Ooijen), Pelupessy, Bel Hassani – Tannane, Weghorst, Darri (28. Gosens).
Subs: Fij – Breukers, Bosz, Gladon, Navrátil, van Ooijen, Gosens.
Coach:
Subs: Olij – J. Wuytens, Hupperts, T. Haye, Mühren, Luckassen, Haps.
Coach:
Heracles Almelo: B. Castro – Droste, te Wierik, Zomer, Fledderus (27. Navrátil) – Bruns (72. van Ooijen), Pelupessy, Bel Hassani – Tannane, Weghorst, Darri (28. Gosens).
Subs: Fij – Breukers, Bosz, Gladon, Navrátil, van Ooijen, Gosens.
Coach:
Referees:
Attendance: