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All times are CEST (UTC + 2)
| Crystal Palace – West Brom | 2:0 (end) | | | Norwich – Leicester | 1:2 (end) | | | Manchester City – Newcastle | 6:1 (end) |
| Aston Villa – Stoke | 0:1 (end) | | | Bournemouth – Watford | 1:1 (end) | | | Sunderland – West Ham | 2:2 (end) |
| Chelsea – Southampton | 1:3 (end) |
| Sevilla – Barcelona | 2:1 (end) | | | Granada – La Coruňa | 1:1 (end) | | | Espanyol – Gijón | 1:2 (end) |
| Las Palmas – Eibar | 0:2 (end) | | | Malaga – Real Sociedad | 3:1 (end) |
| Mönchengladbach – Wolfsburg | 2:0 (end) | | | Hannover – Bremen | 1:0 (end) | | | Hertha – Hamburg | 3:0 (end) |
| Hoffenheim – Stuttgart | 2:2 (end) | | | Ingolstadt – Frankfurt | 2:0 (end) |
| Heracles – Heerenveen | 2:0 (end) | | | Nijmegen – Den Haag | 4:1 (end) | | | Kerkrade – Cambuur | 1:1 (end) |
| Willem II – Zwolle | 0:1 (end) | | | Excelsior – Utrecht | 1:0 (end) |
| Charleroi – Waregem | 3:0 (end) | | | Leuven – Mouscron | 1:1 (end) | | | Westerlo – Kortrijk | 1:1 (end) |
| Sint-Truiden – Waasland-Beveren | 1:3 (end) |
| FC Ferreira – Nacional | 3:1 (end) | | | Tondela – Moreirense | 1:1 (end) | | | Coimbra – Marítimo | 1:0 (end) |
| Rio Ave – Boavista | 1:0 (end) |
| Grödig – Sturm Graz | 3:0 (end) | | | Rheindorf Altach – Austria | 1:2 (end) | | | Wolfsberger – Ried | 1:1 (end) |
| Mattersburg – Admira | 0:4 (end) |
| Saransk – Spartak | 0:1 (end) | | | FC Zenit – Rostov | 3:0 (end) | | | Kuban Krasnodar – Machačkala | 1:1 (end) |
| Mladá Boleslav – Příbram | 4:0 (end) | | | Brno – Teplice | 0:4 (end) | | | Zlín – Jablonec | 2:2 (end) |
| Skalica – Ružomberok | 0:1 (end) | | | Trnava – Myjava | 2:1 (end) | | | Žilina – Podbrezová | 1:3 (end) |
| Trenčín – Michalovce | 2:0 (end) |
Goals:
52. Krohn-Dehli (Gameiro), 58. Iborra (Krohn-Dehli) – 74. Neymar (pen.)
Ball possession: 43 % : 57 %.
Shots on target: 5:8. Shots off target: 5:7. Corners: 7:8. Offsides: 5:1. Fouls: 15:14.
Referees:
Attendance:
Cards: 19. Krychowiak (SEV), 23. Andreolli (SEV), 33. Kolodziejczak (SEV), 74. Trémoulinas (SEV), 76. F. Llorente (SEV) – 28. Busquets (BAR), 48. Mathieu (BAR), 60. Alba (BAR)
Penalty missed:
Ball possession: 43 % : 57 %.
Shots on target: 5:8. Shots off target: 5:7. Corners: 7:8. Offsides: 5:1. Fouls: 15:14.
Sevilla FC:
S. Rico – Coke, Andreolli, Kolodziejczak, Trémoulinas (89. Mariano) – Krychowiak, N'Zonzi – Krohn-Dehli, Iborra, Vitolo – Gameiro (72. F. Llorente).
Subs: Soria – Cristóforo, Mariano, Immobile, Konopljanka, F. Llorente, J. A. Reyes.
Coach:
FC Barcelona: Bravo – Roberto, Piqué, Mathieu (60. Dani Alves), Alba – Rakitić, Busquets, Mascherano – Munir (60. Ramírez), L. Suárez, Neymar.
Subs: ter Stegen – Dani Alves, Bartra, Camára, Gumbau, Douglas, Ramírez.
Coach:
Subs: Soria – Cristóforo, Mariano, Immobile, Konopljanka, F. Llorente, J. A. Reyes.
Coach:
FC Barcelona: Bravo – Roberto, Piqué, Mathieu (60. Dani Alves), Alba – Rakitić, Busquets, Mascherano – Munir (60. Ramírez), L. Suárez, Neymar.
Subs: ter Stegen – Dani Alves, Bartra, Camára, Gumbau, Douglas, Ramírez.
Coach:
Referees:
Attendance:
FC Barcelona substitution: Jérémy Mathieu is replaced by Dani Alves.