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All times are CEST (UTC + 2)
| West Ham – Chelsea | 2:1 (end) | | | Leicester – Crystal Palace | 1:0 (end) | | | Aston Villa – Swansea | 1:2 (end) |
| Stoke – Watford | 0:2 (end) | | | Norwich – West Brom | 0:1 (end) | | | Arsenal – Everton | 2:1 (end) |
| Celta Vigo – Real | 1:3 (end) | | | Granada – Betis | 1:1 (end) | | | Sevilla – Getafe | 5:0 (end) |
| Malaga – La Coruňa | 2:0 (end) |
| Bayern – Kolín nad Rýnem | 4:0 (end) | | | Leverkusen – Stuttgart | 4:3 (end) | | | Hannover – Frankfurt | 1:2 (end) |
| Mohuč – Bremen | 1:3 (end) | | | Darmstadt – Wolfsburg | 0:1 (end) | | | Ingolstadt – Hertha | 0:1 (end) |
| Willem II – Heerenveen | 2:2 (end) | | | Graafschap – Heracles | 0:1 (end) | | | Twente – Eindhoven | 1:3 (end) |
| Kerkrade – Excelsior | 1:2 (end) |
| Mechelen – Waregem | 3:4 (end) | | | Leuven – Waasland-Beveren | 0:2 (end) | | | Westerlo – Lokeren | 1:2 (end) |
| Gent – Oostende | 2:2 (end) |
| Marítimo – FC Ferreira | 0:2 (end) | | | Estoril – Rio Ave | 2:2 (end) | | | Guimarães – Coimbra | 1:1 (end) |
| Mattersburg – Rheindorf Altach | 2:1 (end) | | | Salzburg – Ried | 2:1 (end) | | | Sturm Graz – Wolfsberger | 2:0 (end) |
| Admira – Grödig | 0:0 (end) |
| Ural – Perm | 3:1 (end) | | | Saransk – Kuban Krasnodar | 1:1 (end) | | | FC Zenit – Machačkala | 5:1 (end) |
| Zlín – Teplice | 1:2 (end) | | | Mladá Boleslav – Slovácko | 4:1 (end) | | | Ostrava – Příbram | 0:2 (end) |
| Jablonec – Dukla Praha | 3:3 (end) |
| Trenčín – Zlaté Moravce | 4:1 (end) | | | Michalovce – Podbrezová | 2:0 (end) | | | Slovan Bratislava – Dunajská Streda | 1:0 (end) |
Goals:
35. Gameiro, 45. Gameiro (Konopljanka), 50. Banega (pen.), 60. Gameiro (pen.), 81. Konopljanka (pen.)
Ball possession: 57 % : 43 %.
Shots on target: 13:0. Shots off target: 8:4. Corners: 7:3. Offsides: 5:1. Fouls: 18:15.
Referees:
Attendance:
Cards: 51. Iborra (SEV) – 50. Vigaray (GET), 52. Juan Rodríguez (GET) 60. Vigaray (GET)
Penalty missed:
Ball possession: 57 % : 43 %.
Shots on target: 13:0. Shots off target: 8:4. Corners: 7:3. Offsides: 5:1. Fouls: 18:15.
Sevilla FC:
S. Rico – Mariano, Rami, Kolodziejczak, Trémoulinas – Krychowiak, Banega (65. Krohn-Dehli) – Vitolo, Iborra (C) (62. N'Zonzi), Konopljanka – Gameiro (71. F. Llorente).
Subs: Soria – Andreolli, Coke, Krohn-Dehli, F. Llorente, N'Zonzi, J. A. Reyes.
Coach:
Getafe CF: Guaita – Vigaray, Alexis, Vergini, Lago – Lacen, Juan Rodríguez (62. Damián Suárez) – León (C) (56. Wanderson), Víctor, Sarabia – Šćepović.
Subs: Megyeri – Buendía, Moisés Gómez, Damián Suárez, Velázquez, Cala, Wanderson.
Coach:
Subs: Soria – Andreolli, Coke, Krohn-Dehli, F. Llorente, N'Zonzi, J. A. Reyes.
Coach:
Getafe CF: Guaita – Vigaray, Alexis, Vergini, Lago – Lacen, Juan Rodríguez (62. Damián Suárez) – León (C) (56. Wanderson), Víctor, Sarabia – Šćepović.
Subs: Megyeri – Buendía, Moisés Gómez, Damián Suárez, Velázquez, Cala, Wanderson.
Coach:
Referees:
Attendance:
Scorer from a penalty shot is JEVHEN KONOPLJANKA..
Getafe CF substitution: Juan Rodríguez is replaced by Damián Suárez.
Scorer from a penalty shot is KÉVIN GAMEIRO..
Scorer from a penalty shot is ÉVER BANEGA..
Scorer is KÉVIN GAMEIRO. Assisted by Jevhen Konopljanka..