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All times are CEST (UTC + 2)
| Swansea – Chelsea | 2:2 (end) |
| Gijón – Leganés | 2:1 (end) | | | Valencia – Betis | 2:3 (end) | | | Granada – Eibar | 1:2 (end) |
| La Coruňa – Bilbao | 0:1 (end) |
| Bremen – Augsburg | 1:2 (end) | | | Mohuč – Hoffenheim | 4:4 (end) |
| Feyenoord – Den Haag | 3:1 (end) | | | Groningen – Sparta Rotterdam | 1:1 (end) | | | GA Eagles – Kerkrade | 2:0 (end) |
| Ajax – Arnhem | 1:0 (end) |
| Gent – Lokeren | 3:0 (end) | | | Anderlecht – Charleroi | 3:2 (end) | | | Standard – Genk | 2:0 (end) |
| FC Ferreira – Estoril | 0:0 (end) | | | Marítimo – Rio Ave | 0:1 (end) | | | Braga – Boavista | 3:0 (end) |
| Chaves – Setúbal | 0:0 (end) |
| Admira – Salzburg | 0:4 (end) |
| Ufa – FK Krasnodar | 0:0 (end) | | | Spartak – Lok. Moskva | 1:0 (end) | | | Arsenal Tula – FC Zenit | 0:5 (end) |
| Bohemians 1905 – Brno | 3:0 (end) | | | Jablonec – Dukla Praha | 1:1 (end) | | | Teplice – Slavia | 2:2 (end) |
Goals:
76. Kravec – 44. León, 90+4. Enrich
Referees:
Attendance:
Cards: 81. Pereira (GRN) 33. Riesgo (EIB)
Penalty missed:
Granada CF:
Ochoa – Tito (C), Vezo, Tabanou (46. Angulo), G. Silva – Atzili (65. Carcela-González), Agbo, Samper (46. Kravec), Pereira – Boga, Ponce.
Subs: Olazábal – Angulo, Foulquier, Kravec, Carcela-González, Krhin.
Coach:
SD Eibar: Riesgo – Capa, Gálvez, Lejeune, Luna – Dani García (C), F. Rico – León (56. Enrich), Jota (34. Y. Rodríguez), Peña – Kike García (46. Escalante).
Subs: Y. Rodríguez – Bébé, Enrich, Escalante, Adrián González, dos Santos.
Coach:
Subs: Olazábal – Angulo, Foulquier, Kravec, Carcela-González, Krhin.
Coach:
SD Eibar: Riesgo – Capa, Gálvez, Lejeune, Luna – Dani García (C), F. Rico – León (56. Enrich), Jota (34. Y. Rodríguez), Peña – Kike García (46. Escalante).
Subs: Y. Rodríguez – Bébé, Enrich, Escalante, Adrián González, dos Santos.
Coach:
Referees:
Attendance:
Scorer is SERGI ENRICH.
Scorer is ARTEM KRAVEC.
Scorer is PEDRO LEÓN.