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All times are CEST (UTC + 2)
| Liverpool – Everton | 3:1 (end) | | | Burnley – Tottenham | 0:2 (end) | | | Chelsea – Crystal Palace | 1:2 (end) |
| Hull City – West Ham | 2:1 (end) | | | Leicester – Stoke | 2:0 (end) | | | Man Utd. – West Brom | 0:0 (end) |
| Watford – Sunderland | 1:0 (end) | | | Southampton – Bournemouth | 0:0 (end) |
| Villarreal – Eibar | 2:3 (end) | | | Osasuna – Bilbao | 1:2 (end) | | | Real Sociedad – Leganés | 1:1 (end) |
| Malaga – Atlético | 0:2 (end) |
| Schalke – Dortmund | 1:1 (end) | | | Hamburg – Kolín nad Rýnem | 2:1 (end) | | | Freiburg – Bremen | 2:5 (end) |
| RB Leipzig – Darmstadt | 4:0 (end) | | | Bayern – Augsburg | 6:0 (end) | | | Frankfurt – Mönchengladbach | 0:0 (end) |
| Alkmaar – Groningen | 0:0 (end) | | | Zwolle – Excelsior | 1:1 (end) | | | Sparta Rotterdam – Eindhoven | 0:2 (end) |
| Heracles – Heerenveen | 4:1 (end) | | | Utrecht – Willem II | 2:0 (end) |
| Charleroi – Oostende | 1:1 (end) | | | Kortrijk – Mouscron | 2:1 (end) | | | Sint-Truiden – Waasland-Beveren | 3:0 (end) |
| Eupen – Roeselare | 2:2 (end) | | | St.Gilloise – Mechelen | 3:0 (end) | | | Genk – Lokeren | 4:0 (end) |
| Nacional – Guimarães | 1:2 (end) | | | Tondela – Estoril | 0:2 (end) | | | Boavista – Rio Ave | 0:1 (end) |
| SL Benfica – Porto | 1:1 (end) |
| St. Pölten – Rapid | 1:1 (end) | | | Austria – Admira | 0:2 (end) | | | Sturm Graz – Wolfsberger | 4:0 (end) |
| Mattersburg – Ried | 2:1 (end) |
| Ufa – Lok. Moskva | 0:1 (end) | | | Arsenal Tula – Tomsk | 3:0 (end) |
| Liberec – Karviná | 2:0 (end) | | | Příbram – Bohemians 1905 | 1:0 (end) | | | Zlín – Hr. Králové | 1:3 (end) |
| Jihlava – Slovácko | 0:0 (end) | | | Brno – Dukla Praha | 0:0 (end) | | | Plzeň – Teplice | 2:2 (end) |
| Podbrezová – Slovan Bratislava | 2:3 (end) | | | Senica – Michalovce | 1:0 (end) | | | Zlaté Moravce – Trenčín | 0:2 (end) |
final
Southampton FC
0:0
(0:0)
AFC Bournemouth
Goals:
Ball possession: 61 % : 39 %.
Shots on target: 4:3. Shots off target: 8:7. Corners: 6:3. Offsides: 4:1. Fouls: 14:8.
Referees: Moss – Smart, Halliday
Attendance:
Cards: 90+2. Romeu (SOT)
Penalty missed: 79. Arter (BTH), out
Ball possession: 61 % : 39 %.
Shots on target: 4:3. Shots off target: 8:7. Corners: 6:3. Offsides: 4:1. Fouls: 14:8.
Southampton FC:
Forster – Soares, Stephens, Jošida, Bertrand – S. Davis (C), Romeu – Ward-Prowse (63. Boufal), Tadić (81. McQueen), Redmond – Jay Rodriguez (63. S. Long).
Subs: Hassen – Boufal, Cáceres, Clasie, S. Long, Højbjerg, McQueen.
Coach:
AFC Bournemouth: Boruc – A. Smith, Francis (C), S. Cook, Daniels – Fraser, Surman (46. Arter), Gosling, Pugh – Afobe, J. King (70. Wilshere).
Subs: Allsop – Arter, Cargill, Ibe, Stanislas, Wilshere, B. Smith.
Coach:
Subs: Hassen – Boufal, Cáceres, Clasie, S. Long, Højbjerg, McQueen.
Coach:
AFC Bournemouth: Boruc – A. Smith, Francis (C), S. Cook, Daniels – Fraser, Surman (46. Arter), Gosling, Pugh – Afobe, J. King (70. Wilshere).
Subs: Allsop – Arter, Cargill, Ibe, Stanislas, Wilshere, B. Smith.
Coach:
Referees: Moss – Smart, Halliday
Attendance:
Southampton FC substitution: James Ward-Prowse is replaced by Sofiane Boufal.