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All times are CEST (UTC + 2)
| Crystal Palace – Liverpool | 1:2 (end) | | | West Ham – Southampton | 3:0 (end) | | | Man Utd. – Swansea | 2:0 (end) |
| Newcastle – Huddersfield Town | 1:0 (end) | | | Watford – Bournemouth | 2:2 (end) | | | West Brom – Burnley | 1:2 (end) |
| Everton – Manchester City | 1:3 (end) |
| Girona – Levante | 1:1 (end) | | | Bilbao – Celta Vigo | 1:1 (end) | | | Las Palmas – Real | 0:3 (end) |
| Sevilla – Barcelona | 2:2 (end) |
| Hoffenheim – Kolín nad Rýnem | 6:0 (end) | | | Schalke – Freiburg | 2:0 (end) | | | Leverkusen – Augsburg | 0:0 (end) |
| Hannover – RB Leipzig | 2:3 (end) | | | Stuttgart – Hamburg | 1:1 (end) | | | Bayern – Dortmund | 6:0 (end) |
| Hertha – Wolfsburg | 0:0 (end) |
| Zwolle – Sparta Rotterdam | 2:0 (end) | | | Arnhem – Kerkrade | 0:3 (end) | | | Eindhoven – Breda | 5:1 (end) |
| Willem II – Utrecht | 3:2 (end) | | | Den Haag – Alkmaar | 0:3 (end) |
| Kortrijk – Waasland-Beveren | 4:1 (end) | | | Lierse – Mouscron | 0:3 (end) | | | Lokeren – Sint-Truiden | 1:0 (end) |
| Eupen – Beerschot | 2:2 (end) |
| FC Ferreira – Chaves | 2:0 (end) | | | Portimonense – Moreirense | 4:3 (end) | | | SL Benfica – Guimarães | 2:0 (end) |
| Braga – Sporting | 1:0 (end) |
| Admira – Linz | 0:1 (end) | | | Salzburg – Wolfsberger | 2:0 (end) | | | Austria – Rheindorf Altach | 2:1 (end) |
| St. Pölten – Sturm Graz | 1:5 (end) |
| Perm – Lok. Moskva | 2:1 (end) | | | Grozny – Chabarovsk | 0:0 (end) | | | Dynamo – Arsenal Tula | 2:1 (end) |
| Spartak – Tosno | 2:1 (end) |
| Brno – Karviná | 0:0 (end) | | | Jablonec – Bohemians 1905 | 2:1 (end) | | | Slovácko – Liberec | 0:1 (end) |
| Teplice – Sparta | 1:1 (end) | | | Plzeň – Mladá Boleslav | 1:2 (end) |
| Zlaté Moravce – Senica | 2:2 (end) | | | Žilina – Trenčín | 1:5 (end) | | | Slovan Bratislava – Ružomberok | 1:0 (end) |
Goals:
Ball possession: 51 % : 49 %.
Corners: 4:5. Offsides: 0:3. Fouls: 16:14.
Referees: Aytekin – Dietz, Beitinger
Attendance:
Cards: 84. Duda (HER) – 19. Guilavogui (WOF), 80. Verhaegh (WOF) 90+1. Guilavogui (WOF)
Penalty missed:
Ball possession: 51 % : 49 %.
Corners: 4:5. Offsides: 0:3. Fouls: 16:14.
Hertha BSC:
Almenning Jarstein – Weiser, Stark, Rekik, Mittelstädt – Maier (70. Duda), Lustenberger – Leckie, Darida, Kalou (83. Schieber) – Ibišević (C) (62. Selke).
Subs: Kraft – Duda, Esswein, Pekarík, Selke, Schieber, Skjelbred.
Coach:
VfL Wolfsburg: Casteels – Verhaegh, Bruma, Knoche, William – Camacho (C) – Guilavogui, Arnold – Brekalo (68. Steffen), Dimata (83. Origi), Osimhen (46. Didavi).
Subs: Grün – Bazoer, Didavi, Itter, Jaeckel, Origi, Steffen.
Coach:
Subs: Kraft – Duda, Esswein, Pekarík, Selke, Schieber, Skjelbred.
Coach:
VfL Wolfsburg: Casteels – Verhaegh, Bruma, Knoche, William – Camacho (C) – Guilavogui, Arnold – Brekalo (68. Steffen), Dimata (83. Origi), Osimhen (46. Didavi).
Subs: Grün – Bazoer, Didavi, Itter, Jaeckel, Origi, Steffen.
Coach:
Referees: Aytekin – Dietz, Beitinger
Attendance:
VfL Wolfsburg substitution: Nany Landry Dimata is replaced by Divock Origi.