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All times are CEST (UTC + 2)
| Huddersfield Town – Bournemouth | 0:2 (end) | | | Newcastle – Everton | 3:2 (end) | | | Southampton – Tottenham | 2:1 (end) |
| Manchester City – Watford | 3:1 (end) |
| Alavés – Eibar | 1:1 (end) | | | Atlético – Leganés | 1:0 (end) | | | Barcelona – Rayo Vallecano | 3:1 (end) |
| Getafe – Huesca | 2:1 (end) |
| Bayern – Wolfsburg | 6:0 (end) | | | Dortmund – Stuttgart | 3:1 (end) | | | Freiburg – Hertha | 2:1 (end) |
| RB Leipzig – Augsburg | 0:0 (end) | | | Mohuč – Mönchengladbach | 0:1 (end) |
| Venlo – Excelsior | 1:0 (end) | | | Den Haag – Heerenveen | 2:3 (end) | | | Eindhoven – Breda | 2:0 (end) |
| Willem II – Graafschap | 3:2 (end) |
| Marítimo – Moreirense | 3:2 (end) | | | Braga – Guimarães | 1:0 (end) | | | Boavista – Sporting | 1:2 (end) |
| Samara – Jenisej | 4:0 (end) | | | CSKA Moskva – Kazaň | 3:0 (end) |
| Karviná – Bohemians 1905 | 0:3 (end) | | | Mladá Boleslav – Příbram | 2:0 (end) | | | Zlín – Dukla Praha | 2:1 (end) |
| Opava – Slovácko | 2:2 (end) | | | Sparta – Plzeň | 4:0 (end) |
| Nitra – Ružomberok | 0:0 (end) | | | Sereď – Trnava | 3:1 (end) | | | Michalovce – Trenčín | 4:2 (end) |
| Podbrezová – Žilina | 0:2 (end) | | | Zlaté Moravce – Dunajská Streda | 1:2 (end) | | | Senica – Slovan Bratislava | 1:2 (end) |
final
Southampton FC
2:1
(0:1)
Tottenham Hotspur
Goals:
77. Valery (Armstrong), 81. Ward-Prowse – 26. Kane (Alli)
Ball possession: 37 % : 63 %.
Shots on target: 4:5. Shots off target: 4:9. Corners: 1:10. Offsides: 2:1. Fouls: 16:9.
Referees: Kevin Friend – Matthew Wilkes, Simon Beck
Attendance:
Cards: 10. Romeu (SOT), 23. Valery (SOT), 78. P.-E. Höjbjerg (SOT), 88. Redmond (SOT) – 79. Walker-Peters (TOT), 88. Moussa Sissoko (TOT)
Penalty missed:
Ball possession: 37 % : 63 %.
Shots on target: 4:5. Shots off target: 4:9. Corners: 1:10. Offsides: 2:1. Fouls: 16:9.
Southampton FC:
Gunn – Jošida, Bednarek, Vestergaard – Valery, P.-E. Höjbjerg (C), Romeu (46. S. Long, 73. Armstrong), Bertrand – Ward-Prowse, Redmond – Ch. Austin (46. Sims).
Subs: A. McCarthy – Stephens, Armstrong, Targett, Sims, Slattery, S. Long.
Coach:
Tottenham Hotspur: Lloris (C) – Walker-Peters, D. Sánchez, Vertonghen, Rose (82. Davies) – Dier, Moussa Sissoko – Lucas Moura (72. Son Hung-min), Eriksen, Alli (82. F. Llorente) – Kane.
Subs: Gazzaniga – Davies, Foyth, Lamela, Wanyama, Son Hung-min, F. Llorente.
Coach:
Subs: A. McCarthy – Stephens, Armstrong, Targett, Sims, Slattery, S. Long.
Coach:
Tottenham Hotspur: Lloris (C) – Walker-Peters, D. Sánchez, Vertonghen, Rose (82. Davies) – Dier, Moussa Sissoko – Lucas Moura (72. Son Hung-min), Eriksen, Alli (82. F. Llorente) – Kane.
Subs: Gazzaniga – Davies, Foyth, Lamela, Wanyama, Son Hung-min, F. Llorente.
Coach:
Referees: Kevin Friend – Matthew Wilkes, Simon Beck
Attendance:
Moussa Sissoko (Tottenham Hotspur) is shown a yellow card.
Tottenham Hotspur substitution: Dele Alli is replaced by Fernando Llorente.