Penalty missed:

FC Twente: Marsman – ter Avest, Uvini, Tapia, Schilder – Mokotjo (84. van der Heyden), Gutiérrez, Ziyech (80. Agyepong) – Ede, Oosterwijk (81. Eghan), Cabral.
Subs: Drommel – Agyepong, Hölscher, Andersen, van der Heyden, van der Lely, Eghan.
Coach:

Heracles Almelo: B. Castro – Droste, te Wierik, Zomer (46. van Ooijen), Fledderus – Bruns, Pelupessy, Bel Hassani – Darri, Weghorst (65. Bosz), Gosens (46. Gladon).
Subs: Fij – Bosz, Gladon, Navrátil, van Ooijen, García, Heerkes.
Coach:

Referees: Blom – Langkamp, Balder

Attendance: 28.900

Penalty missed:

KRC Genk: Bizot – Tshimanga, Kabasele, Dewaest, Walsh – Ndidi, Pozuelo, Kebano, Malinovskiy – Buffel, Bailey
Subs: Hamalainen, Kumordzi, Ünal, Gorius, Camargo, Köteles, Karelis
Coach:

SV Zulte-Waregem: Bossut – Sami, Dalsgaard, Verboom, Diallo – Kaya, De Ridder, Lepoint – Buyl, Leye
Subs: Baudry, Benteke, Godeau, Steppe, Cordaro, Essikal, Storm
Coach:

Referees: Laforge – Conotte, Gilon

Attendance:

Penalty missed:

Sporting Lisabon: Patrício – Naldo, Pereira, Ewerton, Jefferson – Mário (90+3. Mané), Carvalho (46. Martins), César (31. Boeck) – Ruiz, Slimani, Silva (C)
Subs: Boeck – Schelotto, Aquilani, Montero, Oliveira, Martins, Mané
Coach:

CD Tondela: Jones – Oto'o, Santos (C) (64. Menga), Thicot, Kaká – Tavares (83. Chamorro), Guzzo, Monteiro – Baldé, Wagner (78. Amado), Junior
Subs: Ramos – Pica, Berger, Amado, Jaquité, Menga, Chamorro
Coach:

Referees:

Attendance: