Penalty missed:

Brighton & Hove Albion: Verbruggen – Lamptey (85. Offiah), Webster, Dunk (C) (46. Barco), Igor – Groß, Gilmour (70. Welbeck) – Buonanotte, Enciso (85. Fati), Adingra – Pedro.
Subs: Steele – Lallana, Moder, Baleba.
Coach: R. De Zerbi.

Chelsea FC: Petrović – Gusto (69. James), Chalobah, Badiashile, Cucurella – Caicedo, Gallagher (C) (90+9. Casadei) – Madueke (69. Sterling), Palmer (90+9. Ugochukwu), Mudryk (42. Nkunku) – N. Jackson.
Subs: Bettinelli – T. Silva, Chilwell, Colwill.
Coach: M. Pochettino.

Referees: Salisbury – West, Eaton

Attendance: 31 555

Penalty missed:

Manchester United: An. Onana – Wan-Bissaka, Casemiro, Evans, Dalot – Mainoo (83. L. Martínez), Amrabat – Amad Diallo (82. Höjlund), McTominay, Garnacho (83. Rashford) – Fernandes (C) (90. Eriksen).
Subs: Bayındır – Collyer, Antony, Forson, Kambwala.
Coach: Erik ten Hag

Newcastle United: Dúbravka – Trippier (C) (63. Schär), Krafth, Burn, L. Hall – Guimarães, Longstaff (77. Barnes), Anderson (62. Joelinton) – J. Murphy (62. Almirón), Isak, A. Gordon.
Subs: Pope – Dummett, A. Murphy, Ritchie, J. White.
Coach: Eddie Howe

Referees: Jones – Hussin, Betts

Attendance:

Penalty missed:

Sevilla FC: Nyland – Navas (C) (84. J. Sánchez), Badé, S. Ramos, Salas – Ocampos (84. M. Díaz), Soumaré, Agoumé, Acuña (89. Pedrosa) – En-Nesyri, Lukebakio (46. Suso).
Subs: Dmitrović, Flores – M. Bueno, Nianzou, Véliz, Jordán, Marcão, Mejbri.
Coach: Sánchez Flores.

Cadiz CF: Ledesma (C) – Zaldúa (81. Alejo), Chust, Fali, J. Hernández (90+1. Ma. Gómez) – Sobrino (61. Jiménez), Alcaraz, Escalante, Navarro (81. Ocampo) – C. Ramos, Martí (61. Guardiola).
Subs: Gil – Mbaye, Machís, Samassékou, Carcelén, Á. Fernández.
Coach: Pellegrino.

Referees: Ortiz – Garrido, Santiago

Attendance:

Penalty missed:

Rayo Vallecano: Dimitrievski – Balliu, Mumin, Lejeune, Espino – Palazón (88. Nteka), Valentín (C) (79. Ciss), U. López (46. Crespo), Á. García (88. K. Pérez) – Camello (65. De Frutos), Trejo.
Subs: Cárdenas – Bebé, Chavarría, de Tomás, Falcao, A. Hernández, Rațiu.
Coach: Iñigo Pérez

Granada CF: M. Martínez – Ri. Sánchez, Rubio, Torrente (73. Rodelas), Neva (C) – Pellistri, S. Ruiz (61. Arezo), Gumbau, Corbeanu (46. Callejón) – Boyé, Melendo (46. G. Villar).
Subs: Batalla, A. López – Bru. Méndez, Hongla, Maouassa, Miquel, Piątkowski.
Coach: Jose Ramon Sandoval

Referees: De Mara Escuderos – Aguado, Ramos

Attendance: 12 738

Penalty missed:

Celta de Vigo: I. Villar (C) – Manquillo, Starfelt, C. Domínguez – C. Pérez (46. Mingueza), Beltrán, Dam. Rodríguez, M. Sánchez (46. H. Álvarez) – Bamba (46. Aspas), Strand Larsen (73. Douvikas), Swedberg (77. Cervi).
Subs: Guaita – Núñez, Tapia, Sotelo, de la Torre, Jailson, M. Rodríguez.
Coach: Giráldez

Athletic Bilbao: Simón (62. Agirrezabala) – Lekue (C), Y. Álvarez, Paredes, de Albéniz – Prados (75. de Galarreta), Dan. García (75. Vesga) – Berenguer, U. Gómez, Ares (62. Raúl García) – Villalibre (62. I. Williams).
Subs: Rincón, Egiluz, Vivian, de Marcos, A. Herrera, Jauregizar, Olabarrieta.
Coach: Valverde

Referees: V. García – Méndez, Villaseñor

Attendance: 21 301

Penalty missed:

Getafe CF: Soria (C) – Maksimović, Alderete, G. Álvarez – Carmona, Moriba (46. Mata), Milla (57. Santiago), Rico (46. Jor. Martín) – Ó. Rodríguez (70. Risco), Greenwood – Aleñá (46. Latasa).
Subs: Fuzato – Aberdin, Angileri.
Coach: José Bordalás

Atlético Madrid: Oblak – Llorente (87. Mandava), Giménez, Witsel, Hermoso, Lino (76. Saúl) – Koke (C), de Paul, Barrios (46. Azpilicueta) – Correa (67. Riquelme), Griezmann (87. Depay).
Subs: Moldovan, Gomis – Gabriel, Savić, Morata, Vermeeren.
Coach: Diego Simeone

Referees: Melero – Martínez, García

Attendance: 13 027