Penalty missed:

SC Cambuur Leeuwarden: Zeinstra – Anderson, Peersman, Dammers, Andriuškevičius – Barto, Overgoor, J. Byrne (61. Monteiro) – F. Narsingh (83. Houtkoop), Berisha (46. Ogbeche), M. Rosheuvel.
Subs: Nienhuis – Pereira, Mac-Intosch, Mašek, Houtkoop, Ogbeche, Monteiro.
Coach:

Twente Enschede: Drommel – ter Avest, Uvini, Bijen, Schilder – Mokotjo, Ziyech, Gutiérrez – Ede (90+2. Hölscher), Olaitan, Cabral (85. da Cruz).
Subs: Marsman – Andersen, van der Lely, Hölscher, van der Heyden, da Cruz, Oosterwijk.
Coach:

Referees:

Attendance:

Penalty missed:

PEC Zwolle: Begois – van Polen (C), Marcellis, Lam, van Hintum – Dekker, Bouy – Becker, Thomas (71. Lazić), Mennig (61. Marinus) – Veldwijk (81. Nijland).
Subs: van der Hart – Sainsbury, Nijland, Marinus, El Hasnaoui, Lazić, Brama.
Coach:

HFC ADO Den Haag: Hansen – Ebuehi (74. Jansen), Wormgoor, Zuiverloon (81. Korte), Meijers (C) – Malone, Alberg (75. Kristensen), D. Bakker – Schaken, Havenaar, Duplan.
Subs: Zwinkels – Derijck, Kristensen, Jansen, Gorré, Korte, Kastaneer.
Coach:

Referees: Janssen

Attendance:

Penalty missed:

Heracles Almelo: B. Castro – Droste, te Wierik, Zomer, Fledderus – Bruns, Pelupessy, Bel Hassani – Tannane (73. Gosens), Weghorst (84. Gladon), Darri (74. van Ooijen).
Subs: Fij – Bosz, van Ooijen, Navrátil, Gladon, Breukers, Gosens.
Coach:

PSV Eindhoven: Zoet – Arias, Bruma, H. Moreno, Brenet (80. S. Poulsen) – Pröpper, Hendrix, Maher (74. Pereiro) – L. Narsingh (46. Locadia), L. de Jong, Lestienne.
Subs: Pasveer – Locadia, Pereiro, Schaars, Vloet, De Wijs, S. Poulsen.
Coach:

Referees:

Attendance:

Penalty missed:

Willem II Tilburg: Lamprou – van der Struijk, Koppers, D. Wuytens, Peters (C) – Ojo, S. Wuytens – van der Velden (58. de Sa), Haemhouts, Andersen (90. Braber) – Falkenburg (83. Nemec).
Subs: Meul – Ligeon, Braber, de Sa, Joppen, Kuiper, Nemec.
Coach:

FC Utrecht: Ruiter – Letschert, Nganioni, van der Maarel, Klaiber (75. Leeuwin), Strieder – W. Janssen (C), Ayoub, Ramselaar (86. Ludwig) – Haller, Barazite.
Subs: Bednarek – Leeuwin, Ludwig, Diemers, Peterson, Rubin.
Coach:

Referees:

Attendance: