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| Norwich – Swansea | 1:0 (end) | | | Leicester – Watford | 2:1 (end) | | | Man Utd. – West Brom | 2:0 (end) |
| Stoke – Chelsea | 1:0 (end) |
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| Rayo Vallecano – Granada | 2:1 (end) | | | Malaga – Betis | 0:1 (end) |
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| Hoffenheim – Frankfurt | 0:0 (end) | | | Mohuč – Wolfsburg | 2:0 (end) | | | Darmstadt – Hamburg | 1:1 (end) |
| Twente – Heerenveen | 1:4 (end) | | | Nijmegen – Graafschap | 2:0 (end) | | | Willem II – Excelsior | 2:3 (end) |
| Zwolle – Heracles | 1:1 (end) |
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| Kortrijk – Mechelen | 1:0 (end) |
| Guimarães – Nacional | 0:1 (end) |
| Austria – Salzburg | 1:1 (end) | | | Sturm Graz – Ried | 3:2 (end) | | | Wolfsberger – Mattersburg | 2:1 (end) |
| Admira – Rheindorf Altach | 1:1 (end) |
| Ural – Rostov | 1:2 (end) | | | Ufa – Perm | 2:1 (end) | | | Dynamo – Kuban Krasnodar | 2:1 (end) |
| Grozny – Spartak | 2:1 (end) |
| Dukla Praha – Příbram | 0:1 (end) | | | Zlín – Slovácko | 2:1 (end) | | | Mladá Boleslav – Jihlava | 6:1 (end) |
| Slovan Bratislava – Senica | 2:1 (end) | | | Michalovce – Myjava | 1:2 (end) | | | Podbrezová – Zlaté Moravce | 2:2 (end) |
| Žilina – Ružomberok | 2:0 (end) |
final
FC Twente
1:4
(0:2)
SC Heerenveen
Goals:
64. Ziyech – 6. Slagveer, 40. Otigba, 78. Andersen (own), 85. Sam Larsson
Referees: Jochem Kamphuis – Balder, Lapar (vš. Nizozemsko)
Attendance:
Cards: 56. Oosterwijk (TWE) – 14. Bijker (HEE), 22. van den Berg (HEE), 27. Otigba (HEE), 68. van Anholt (HEE)
Penalty missed: 15. Ziyech (TWE), out
FC Twente:
Drommel – ter Avest (72. Olaitan), Uvini, Andersen, van der Lely – Mokotjo, Ziyech (C), Gutiérrez – Agyepong (80. Hölscher), Oosterwijk, Ede (46. Eghan).
Subs: Verrips – Olaitan, Hölscher, Eghan, Bijen, van der Heyden.
Coach:
SC Heerenveen: Mulder – van Anholt, Otigba (87. Buijs), van den Berg (C), Bijker – Slagveer (87. Zahovič), St. Juste, Thorsby (71. Thern), Cavlan – te Vrede, Sam Larsson.
Subs: De Fockert – Kada, Zahovič, Buijs, Marzo, van den Boomen, Thern.
Coach:
Subs: Verrips – Olaitan, Hölscher, Eghan, Bijen, van der Heyden.
Coach:
SC Heerenveen: Mulder – van Anholt, Otigba (87. Buijs), van den Berg (C), Bijker – Slagveer (87. Zahovič), St. Juste, Thorsby (71. Thern), Cavlan – te Vrede, Sam Larsson.
Subs: De Fockert – Kada, Zahovič, Buijs, Marzo, van den Boomen, Thern.
Coach:
Referees: Jochem Kamphuis – Balder, Lapar (vš. Nizozemsko)
Attendance:
SC Heerenveen substitution: Luciano Slagveer is replaced by Luka Zahovič.