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All times are CEST (UTC + 2)
| Bournemouth – Newcastle | 0:1 (end) | | | West Ham – Everton | 1:1 (end) | | | Sunderland – Southampton | 0:1 (end) |
| Norwich – Swansea | 1:0 (end) | | | Leicester – Watford | 2:1 (end) | | | Man Utd. – West Brom | 2:0 (end) |
| Stoke – Chelsea | 1:0 (end) |
| Celta Vigo – Valencia | 1:5 (end) | | | Levante – La Coruňa | 1:1 (end) | | | Eibar – Getafe | 3:1 (end) |
| Rayo Vallecano – Granada | 2:1 (end) | | | Malaga – Betis | 0:1 (end) |
| Bayern – Stuttgart | 4:0 (end) | | | Leverkusen – Kolín nad Rýnem | 1:2 (end) | | | Mönchengladbach – Ingolstadt | 0:0 (end) |
| Hoffenheim – Frankfurt | 0:0 (end) | | | Mohuč – Wolfsburg | 2:0 (end) | | | Darmstadt – Hamburg | 1:1 (end) |
| Twente – Heerenveen | 1:4 (end) | | | Nijmegen – Graafschap | 2:0 (end) | | | Willem II – Excelsior | 2:3 (end) |
| Zwolle – Heracles | 1:1 (end) |
| Oostende – Leuven | 3:0 (end) | | | Lokeren – Sint-Truiden | 1:1 (end) | | | Waasland-Beveren – Westerlo | 2:2 (end) |
| Kortrijk – Mechelen | 1:0 (end) |
| Guimarães – Nacional | 0:1 (end) |
| Austria – Salzburg | 1:1 (end) | | | Sturm Graz – Ried | 3:2 (end) | | | Wolfsberger – Mattersburg | 2:1 (end) |
| Admira – Rheindorf Altach | 1:1 (end) |
| Ural – Rostov | 1:2 (end) | | | Ufa – Perm | 2:1 (end) | | | Dynamo – Kuban Krasnodar | 2:1 (end) |
| Grozny – Spartak | 2:1 (end) |
| Dukla Praha – Příbram | 0:1 (end) | | | Zlín – Slovácko | 2:1 (end) | | | Mladá Boleslav – Jihlava | 6:1 (end) |
| Slovan Bratislava – Senica | 2:1 (end) | | | Michalovce – Myjava | 1:2 (end) | | | Podbrezová – Zlaté Moravce | 2:2 (end) |
| Žilina – Ružomberok | 2:0 (end) |
Goals:
1. Živković, 19. D. Wuytens – 2. van Weert, 29. Stans (pen.), 58. van Mieghem
Ball possession: 57 % : 43 %.
Shots on target: 3:4. Shots off target: 11:6. Corners: 3:5. Offsides: 3:1. Fouls: 12:17.
Referees: van Boekel – Boonman, Ketting
Attendance:
Cards: 31. Ojo (WLM), 65. Peters (WLM) – 33. van Mieghem (EXC), 40. van Weert (EXC)
Penalty missed:
Ball possession: 57 % : 43 %.
Shots on target: 3:4. Shots off target: 11:6. Corners: 3:5. Offsides: 3:1. Fouls: 12:17.
Willem II Tilburg:
Lamprou – van der Struijk, D. Wuytens, Peters, Koppers (77. Braber) – Ojo, Falkenburg (62. de Sa), S. Wuytens – Živković (81. van der Velden), Nemec, Andersen.
Subs: Meul – Ligeon, Braber, de Sa, van der Velden, Joppen, Heerkens.
Coach:
SBV Excelsior: Muyters – Karami, Fischer, Mattheij, Kuipers – Kruijs, Stans, Auassar – Kuwas (90+1. Vermeulen) – van Weert, van Mieghem (77. Elbers).
Subs: Kurto – van Diermen, Hasselbaink, Vermeulen, H. Drost, Bovenberg, Elbers.
Coach:
Subs: Meul – Ligeon, Braber, de Sa, van der Velden, Joppen, Heerkens.
Coach:
SBV Excelsior: Muyters – Karami, Fischer, Mattheij, Kuipers – Kruijs, Stans, Auassar – Kuwas (90+1. Vermeulen) – van Weert, van Mieghem (77. Elbers).
Subs: Kurto – van Diermen, Hasselbaink, Vermeulen, H. Drost, Bovenberg, Elbers.
Coach:
Referees: van Boekel – Boonman, Ketting
Attendance:
SBV Excelsior substitution: Daryl van Mieghem is replaced by Stanley Elbers.