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| Swansea – Liverpool | 3:1 (end) | | | Man Utd. – Leicester | 1:1 (end) | | | Southampton – Manchester City | 4:2 (end) |
| Granada – Las Palmas | 3:2 (end) | | | Bilbao – Celta Vigo | 2:1 (end) | | | Espanyol – Sevilla | 1:0 (end) |
| La Coruňa – Getafe | 0:2 (end) | | | Valencia – Villarreal | 0:2 (end) |
| Heerenveen – Groningen | 1:2 (end) | | | Alkmaar – Graafschap | 4:1 (end) | | | Willem II – Feyenoord | 0:1 (end) |
| Ajax – Twente | 4:0 (end) | | | Eindhoven – Cambuur | 6:2 (end) | | | Excelsior – Zwolle | 2:2 (end) |
| Heracles – Den Haag | 1:1 (end) | | | Arnhem – Utrecht | 1:3 (end) | | | Nijmegen – Kerkrade | 1:2 (end) |
| Anderlecht – Gent | 2:0 (end) | | | Club Bruggy – Genk | 3:1 (end) |
| Moreirense – Boavista | 1:1 (end) | | | Estoril – Marítimo | 2:1 (end) | | | Arouca – Nacional | 3:0 (end) |
| União Madeira – Coimbra | 3:1 (end) |
| Austria – Salzburg | 0:2 (end) |
| Ufa – Kazaň | 1:1 (end) | | | Saransk – Rostov | 2:1 (end) | | | Grozny – Samara | 0:1 (end) |
| FK Krasnodar – Machačkala | 3:0 (end) |
| Teplice – Sparta | 1:1 (end) | | | Bohemians 1905 – Slavia | 0:0 (end) |
| Skalica – Myjava | 1:2 (end) |
final
Ajax Amsterdam
4:0
(1:0)
FC Twente
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90+2
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Game over.
(16:21:35)
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86. Amin Younes (AJA) - 4:0
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86
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Team Ajax with just scored a goal! Scorer is AMIN YOUNES.
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82. Viktor Fischer (AJA) - 3:0
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82
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Team Ajax with just scored a goal! Scorer is VIKTOR FISCHER.
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81
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Ajax Amsterdam substitution: Václav Černý is replaced by Viktor Fischer.
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80. Mike van der Hoorn (AJA) - 2:0
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80
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Team Ajax with just scored a goal! Scorer is MIKE VAN DER HOORN.
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76
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FC Twente substitution: Robbert Schilder is replaced by Tim Hölscher.
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76
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Ajax Amsterdam substitution: Kenny Tete is replaced by Jaïro Riedewald.
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75
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Ajax Amsterdam substitution: Thulani Serero is replaced by Riechedly Bazoer.
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69
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Hakim Ziyech (FC Twente) is shown a yellow card.
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68
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Peet Bijen (FC Twente) is shown a yellow card.
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55.
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46
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Start of 2nd half.
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45+1
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1st halftime finished.
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43
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Nick Viergever (Ajax Amsterdam) is shown a yellow card.
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37. Václav Černý (AJA) - 1:0
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37
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Team Ajax with just scored a goal! Scorer is VÁCLAV ČERNÝ.
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Goals:
37. Černý, 80. van der Hoorn, 82. Fischer, 86. Younes
Referees: Blom – Langkamp, van Zuilen
Attendance: 51 772
Cards: 43. Viergever (AJA) – 68. Bijen (TWE), 69. Ziyech (TWE)
Penalty missed:
Ajax Amsterdam:
Cillessen – Veltman, van der Hoorn, Viergever, Tete (76. Riedewald) – Serero (75. Bazoer), Klaassen, Gudelj – Černý (81. Fischer), Milik, Younes.
Subs: Boer – van Rhijn, Bazoer, Fischer, Sinkgraven, Schøne, Riedewald.
Coach:
FC Twente: Marsman – ter Avest, Bijen, Uvini, Thesker – Mokotjo, Ziyech, Schilder (76. Hölscher) – Cabral, El Azzouzi, Ede.
Subs: Stevens – Gutiérrez, Zawada, Børven, Hölscher, van der Heyden, van der Lely.
Coach:
Subs: Boer – van Rhijn, Bazoer, Fischer, Sinkgraven, Schøne, Riedewald.
Coach:
FC Twente: Marsman – ter Avest, Bijen, Uvini, Thesker – Mokotjo, Ziyech, Schilder (76. Hölscher) – Cabral, El Azzouzi, Ede.
Subs: Stevens – Gutiérrez, Zawada, Børven, Hölscher, van der Heyden, van der Lely.
Coach:
Referees: Blom – Langkamp, van Zuilen
Attendance: 51 772