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| Liverpool – Burnley | 2:1 (end) |
| Real Sociedad – Bilbao | 0:2 (end) | | | La Coruňa – Barcelona | 2:1 (end) | | | Celta Vigo – Villarreal | 0:1 (end) |
| Real – Betis | 2:1 (end) |
| Schalke – Augsburg | 3:0 (end) | | | Hamburg – Mönchengladbach | 2:1 (end) |
| Willem II – Zwolle | 2:0 (end) | | | Feyenoord – Alkmaar | 5:2 (end) | | | Kerkrade – Groningen | 3:1 (end) |
| Ajax – Twente | 3:0 (end) |
| Club Bruggy – Sint-Truiden | 2:2 (end) | | | Anderlecht – Waasland-Beveren | 3:0 (end) | | | Standard – Oostende | 2:2 (end) |
| Gent – Mechelen | 3:0 (end) | | | Kortrijk – Mouscron | 0:2 (end) | | | Eupen – Waregem | 1:3 (end) |
| Lokeren – Charleroi | 0:0 (end) | | | Westerlo – Genk | 0:4 (end) |
| Boavista – Marítimo | 3:0 (end) | | | Rio Ave – Moreirense | 3:2 (end) | | | Guimarães – Estoril | 3:3 (end) |
| Sturm Graz – Rapid | 2:1 (end) |
| Perm – FC Zenit | 1:0 (end) | | | Spartak – Machačkala | 1:0 (end) | | | Rostov – Grozny | 0:0 (end) |
| Mladá Boleslav – Sparta | 1:0 (end) | | | Slavia – Teplice | 2:1 (end) |
| Trenčín – Michalovce | 4:1 (end) | | | Podbrezová – Trnava | 0:1 (end) |
final
Real Madrid
2:1
(1:1)
Real Betis
Goals:
41. Ronaldo (Marcelo), 81. Ramos (Kroos) – 25. Navas (own)
Ball possession: 69 % : 31 %.
Shots on target: 4:3. Shots off target: 9:4. Corners: 8:4. Offsides: 7:2. Fouls: 8:21.
Referees: Mateu – Cebrián, Nunez
Attendance: 73 103
Cards: 87. Marcelo (REA) – 30. Piccini (RBE) 78. Piccini (RBE)
Penalty missed:
Ball possession: 69 % : 31 %.
Shots on target: 4:3. Shots off target: 9:4. Corners: 8:4. Offsides: 7:2. Fouls: 8:21.
Real Madrid:
Navas – Carvajal, Nacho Fernández, Ramos (C), Marcelo – Modrić, Kroos, Isco – James Rodríguez (69. L. Vázquez), Morata (71. Benzema), Ronaldo.
Subs: Casilla – Benzema, Casemiro, Kovačić, L. Vázquez, Asensio, Danilo.
Coach:
Real Betis: Adán (C) – Piccini, Mandi (84. R. Navarro), Pezzella, Tosca, Durmisi – Brašanac (86. Alegría), Pardo, D. Ceballos – A. Sanabria, Rubén Castro (64. Petros).
Subs: D. Giménez – R. Navarro, Á. Martínez, Petros, Donk, Joaquín, Alegría.
Coach:
Subs: Casilla – Benzema, Casemiro, Kovačić, L. Vázquez, Asensio, Danilo.
Coach:
Real Betis: Adán (C) – Piccini, Mandi (84. R. Navarro), Pezzella, Tosca, Durmisi – Brašanac (86. Alegría), Pardo, D. Ceballos – A. Sanabria, Rubén Castro (64. Petros).
Subs: D. Giménez – R. Navarro, Á. Martínez, Petros, Donk, Joaquín, Alegría.
Coach:
Referees: Mateu – Cebrián, Nunez
Attendance: 73 103
Scorer is SERGIO RAMOS. Assisted by Toni Kroos.
Scorer is CRISTIANO RONALDO. Assisted by Marcelo.
Own goal scorer is KEYLOR NAVAS.