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All times are CEST (UTC + 2)
| West Brom – Liverpool | 2:2 (end) | | | Watford – Crystal Palace | 0:0 (end) |
| Eibar – Getafe | 0:1 (end) | | | Celta Vigo – Valencia | 1:1 (end) |
| Sevilla – Barcelona | 0:5 (end) |
| RB Leipzig – Hoffenheim | 2:5 (end) | | | Frankfurt – Hertha | 0:3 (end) | | | Hamburg – Freiburg | 1:0 (end) |
| Hannover – Bayern | 0:3 (end) | | | Stuttgart – Bremen | 2:0 (end) | | | Dortmund – Leverkusen | 4:0 (end) |
| Leuven – Mouscron | 3:1 (end) | | | Sint-Truiden – Eupen | 2:3 (end) | | | Waasland-Beveren – Lierse | 0:1 (end) |
| Genk – Anderlecht | 2:1 (end) |
| FC Ferreira – Belenenses | 1:1 (end) | | | Feirense – Guimarães | 2:1 (end) | | | Estoril – SL Benfica | 1:2 (end) |
| Wolfsberger – Sturm Graz | 2:1 (end) | | | Mattersburg – St. Pölten | 1:1 (end) | | | Linz – Austria | 1:0 (end) |
| Kazaň – Rostov | 1:1 (end) | | | Machačkala – Ural | 0:1 (end) |
| Olomouc – Ostrava | 1:0 (end) | | | Slovácko – Dukla Praha | 2:0 (end) | | | Bohemians 1905 – Jihlava | 1:1 (end) |
| Mladá Boleslav – Zlín | 0:1 (end) | | | Brno – Plzeň | 1:3 (end) |
| Ružomberok – Trnava | 0:0 (end) | | | Senica – Podbrezová | 1:0 (end) | | | Zlaté Moravce – Michalovce | 2:2 (end) |
| Man Utd. – Tottenham | 2:1 (end) |
final
Sevilla FC
0:5
(0:3)
FC Barcelona
Goals:
14. Luis Suárez, 31. Messi, 40. Suárez, 53. Iniesta, 69. Coutinho (pen.)
Ball possession: 35 % : 65 %.
Shots on target: 5:9. Shots off target: 5:2. Corners: 2:7. Offsides: 2:4. Fouls: 17:9.
Referees: Manzano
Attendance:
Cards: 34. Mercado (SEV), 38. Escudero (SEV), 75. Vázquez (SEV) – 67. Iniesta (BAR)
Penalty missed:
Ball possession: 35 % : 65 %.
Shots on target: 5:9. Shots off target: 5:2. Corners: 2:7. Offsides: 2:4. Fouls: 17:9.
Sevilla FC:
Soria – Navas, Mercado, Lenglet, Escudero (C) – N´Zonzi, Banega – Sarabia, Vázquez, Muriel – Correa
Subs: Rico – Ramiréz, Pizarro, Layún, Nolito, Carrico, Ben Yedder
Coach:
FC Barcelona: Cillessen – Roberto, Piqué, Umtiti, Alba – Coutinho, Busquets, Rakitič, Iniesta (C) – Messi, Luis Suárez
Subs: ter Stegen – Paulinho, Dembélé, Paco, Semedo, Denis Suárez, Vermaelen
Coach:
Subs: Rico – Ramiréz, Pizarro, Layún, Nolito, Carrico, Ben Yedder
Coach:
FC Barcelona: Cillessen – Roberto, Piqué, Umtiti, Alba – Coutinho, Busquets, Rakitič, Iniesta (C) – Messi, Luis Suárez
Subs: ter Stegen – Paulinho, Dembélé, Paco, Semedo, Denis Suárez, Vermaelen
Coach:
Referees: Manzano
Attendance:
Sevilla FC substitution: Pablo Sarabia is replaced by Miguel Layún.