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| Burnley – Chelsea | 0:4 (end) | | | Crystal Palace – Arsenal | 2:2 (end) | | | Man Utd. – Everton | 2:1 (end) |
| Getafe – Betis | 2:0 (end) | | | Barcelona – Real | 5:1 (end) | | | Alavés – Villarreal | 2:1 (end) |
| Sevilla – Huesca | 2:1 (end) |
| Norimberk – Frankfurt | 1:1 (end) | | | RB Leipzig – Schalke | 0:0 (end) | | | Bremen – Leverkusen | 2:6 (end) |
| Arnhem – Sittard | 2:1 (end) | | | Ajax – Feyenoord | 3:0 (end) | | | Willem II – Utrecht | 0:1 (end) |
| Alkmaar – Heerenveen | 2:3 (end) |
| Standard – Genk | 1:1 (end) | | | Eupen – Anderlecht | 2:1 (end) | | | Waasland-Beveren – Antwerp | 0:1 (end) |
| Moreirense – Marítimo | 1:0 (end) | | | Tondela – Setúbal | 1:2 (end) | | | Porto – Feirense | 2:0 (end) |
| Sporting – Boavista | 3:0 (end) |
| Wolfsberger – St. Pölten | 1:0 (end) | | | Rapid – Admira | 2:0 (end) | | | Linz – Salzburg | 3:3 (end) |
| Jenisej – Lok. Moskva | 0:3 (end) | | | Grozny – Dynamo | 0:0 (end) | | | CSKA Moskva – FK Krasnodar | 1:2 (end) |
| Plzeň – Slovácko | 2:1 (end) | | | Jablonec – Liberec | 0:0 (end) |
| Zlaté Moravce – Trnava | 1:1 (end) |
Goals:
87. W. Janssen
Ball possession: 52 % : 48 %.
Shots on target: 0:8. Shots off target: 7:8. Corners: 9:6. Offsides: 1:2. Fouls: 20:10.
Referees: Kamphuis – Kleinjan, Lapar
Attendance:
Cards: 41. Llonch (WLM), 81. Palacios (WLM)
Penalty missed:
Ball possession: 52 % : 48 %.
Shots on target: 0:8. Shots off target: 7:8. Corners: 9:6. Offsides: 1:2. Fouls: 20:10.
Willem II Tilburg:
Wellenreuther – Dankerlui, Heerkens, Meißner, Palacios – Anita (75. Lieftink), Crowley, Llonch – Saddiki (78. McGarry), Sol, Avdijaj (82. Kristinsson Ingi).
Subs: Woud – Peters, Lieftink, Croux, Kristinsson Ingi, McGarry, van den Bogert.
Coach:
FC Utrecht: D. Jensen – Klaiber, Letschert, W. Janssen, Gavory – van Overeem, Simon Gustafson, Emanuelson – Kerk, Görtler (86. Venema), Tannane (75. van de Streek).
Subs: Paes – van der Maarel, Guwara, Bergström, van de Streek, Velanas, Boussaid, Venema.
Coach:
Subs: Woud – Peters, Lieftink, Croux, Kristinsson Ingi, McGarry, van den Bogert.
Coach:
FC Utrecht: D. Jensen – Klaiber, Letschert, W. Janssen, Gavory – van Overeem, Simon Gustafson, Emanuelson – Kerk, Görtler (86. Venema), Tannane (75. van de Streek).
Subs: Paes – van der Maarel, Guwara, Bergström, van de Streek, Velanas, Boussaid, Venema.
Coach:
Referees: Kamphuis – Kleinjan, Lapar
Attendance:
FC Utrecht substitution: Usáma Tannane is replaced by Sander van de Streek.