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All times are CEST (UTC + 2)
| Bournemouth – Liverpool | 0:4 (end) | | | Arsenal – Huddersfield Town | 1:0 (end) | | | West Ham – Crystal Palace | 3:2 (end) |
| Chelsea – Manchester City | 2:0 (end) | | | Leicester – Tottenham | 0:2 (end) |
| Atlético – Alavés | 3:0 (end) | | | Valencia – Sevilla | 1:1 (end) | | | Villarreal – Celta Vigo | 2:3 (end) |
| Espanyol – Barcelona | 0:4 (end) |
| Bayern – Norimberk | 3:0 (end) | | | Freiburg – RB Leipzig | 3:0 (end) | | | Leverkusen – Augsburg | 1:0 (end) |
| Schalke – Dortmund | 1:2 (end) | | | Wolfsburg – Hoffenheim | 2:2 (end) | | | Hertha – Frankfurt | 1:0 (end) |
| Willem II – Heerenveen | 1:5 (end) | | | Zwolle – Ajax | 1:4 (end) | | | Den Haag – Graafschap | 0:0 (end) |
| Genk – Kortrijk | 1:1 (end) | | | Mouscron – Waregem | 0:0 (end) | | | Oostende – Lokeren | 1:0 (end) |
| Sint-Truiden – Standard | 1:1 (end) |
| Belenenses – Chaves | 1:0 (end) | | | Tondela – Braga | 0:1 (end) | | | Setúbal – SL Benfica | 0:1 (end) |
| Wolfsberger – Linec | 1:1 (end) | | | Admira – Salzburg | 2:2 (end) | | | St. Pölten – Rheindorf Altach | 2:1 (end) |
| Samara – Rostov | 1:0 (end) | | | CSKA Moskva – Jenisej | 2:1 (end) | | | Lok. Moskva – Orenburg | 2:1 (end) |
| Machačkala – Spartak | 0:3 (end) |
| Ostrava – Bohemians 1905 | 2:0 (end) | | | Olomouc – Slovácko | 1:0 (end) | | | Karviná – Jablonec | 2:1 (end) |
| Slavia – Mladá Boleslav | 3:2 (end) |
| Slovan Bratislava – Žilina | 5:2 (end) | | | Podbrezová – Michalovce | 0:1 (end) | | | Senica – Ružomberok | 1:1 (end) |
| Trnava – Trenčín | 3:1 (end) |
final
Leicester City
0:2
(0:1)
Tottenham Hotspur
Goals:
45+1. Son Hung-min (Aurier), 58. Alli (Son Hung-min)
Ball possession: 42 % : 58 %.
Shots on target: 3:2. Shots off target: 5:4. Corners: 6:5. Offsides: 3:1. Fouls: 12:7.
Referees: Craig Pawson – Lee Betts, Ian Hussin
Attendance: 31 957
Cards: 16. N. Mendy (LEC), 64. Albrighton (LEC), 81. Gray (LEC) – 9. Dier (TOT)
Penalty missed:
Ball possession: 42 % : 58 %.
Shots on target: 3:2. Shots off target: 5:4. Corners: 6:5. Offsides: 3:1. Fouls: 12:7.
Leicester City:
Schmeichel – R. Pereira, Morgan (C), J. Evans, Chilwell – N. Mendy (79. Okazaki), Ndidi, Iborra (56. R. Ghezzal) – Maddison, Gray – Iheanacho (56. Albrighton).
Subs: D. Ward – Fuchs, Maguire, Choudhury, Albrighton, R. Ghezzal, Okazaki.
Coach:
Tottenham Hotspur: Lloris (C) – Aurier (78. Walker-Peters), Alderweireld, Vertonghen, Davies – Winks, Dier – Moussa Sissoko, Alli, Son Hung-min (74. Kane) – Lucas Moura (67. Eriksen).
Subs: Gazzaniga – Rose, Walker-Peters, Eriksen, N'Koudou, Kane, Skipp.
Coach:
Subs: D. Ward – Fuchs, Maguire, Choudhury, Albrighton, R. Ghezzal, Okazaki.
Coach:
Tottenham Hotspur: Lloris (C) – Aurier (78. Walker-Peters), Alderweireld, Vertonghen, Davies – Winks, Dier – Moussa Sissoko, Alli, Son Hung-min (74. Kane) – Lucas Moura (67. Eriksen).
Subs: Gazzaniga – Rose, Walker-Peters, Eriksen, N'Koudou, Kane, Skipp.
Coach:
Referees: Craig Pawson – Lee Betts, Ian Hussin
Attendance: 31 957
Leicester City substitution: Vicente Iborra is replaced by Rachid Ghezzal.