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All times are CEST (UTC + 2)
| Burnley – Arsenal | 1:3 (end) | | | Crystal Palace – Bournemouth | 5:3 (end) | | | Leicester – Chelsea | 0:0 (end) |
| Liverpool – Wolverhampton | 2:0 (end) | | | Southampton – Huddersfield Town | 1:1 (end) | | | Tottenham – Everton | 2:2 (end) |
| Watford – West Ham | 1:4 (end) |
| Bilbao – Celta Vigo | 3:1 (end) | | | Atlético – Sevilla | 1:1 (end) | | | Barcelona – Getafe | 2:0 (end) |
| Betis – Huesca | 2:1 (end) | | | Girona – Levante | 1:2 (end) | | | Leganés – Espanyol | 0:2 (end) |
| Real Sociedad – Real | 3:1 (end) | | | Valencia – Alavés | 3:1 (end) | | | Rayo Vallecano – Valladolid | 1:2 (end) |
| Villarreal – Eibar | 1:0 (end) |
| Frankfurt – Mohuč | 0:2 (end) |
| Ajax – Utrecht | 4:1 (end) | | | Alkmaar – Eindhoven | 1:0 (end) | | | Feyenoord – Den Haag | 0:2 (end) |
| Groningen – Sittard | 3:0 (end) | | | Heerenveen – Breda | 2:1 (end) | | | Heracles – Excelsior | 4:5 (end) |
| Arnhem – Graafschap | 6:1 (end) | | | Willem II – Emmen | 2:3 (end) | | | Zwolle – Venlo | 2:4 (end) |
| Antwerp – Anderlecht | 1:1 (end) | | | Club Bruggy – Genk | 3:2 (end) | | | Sint-Truiden – Eupen | 2:2 (end) |
| Guimarães – Belenenses | 5:1 (end) | | | Chaves – Setúbal | 1:2 (end) | | | Nacional – Porto | 0:4 (end) |
| Rio Ave – SL Benfica | 2:3 (end) |
| Wolfsberger – St. Pölten | 4:0 (end) | | | Sturm Graz – Austria | 1:3 (end) | | | Salzburg – Linec | 2:1 (end) |
| Spartak – Ufa | 1:0 (end) | | | FC Zenit – CSKA Moskva | 3:1 (end) |
| Kayserispor – Kasımpaşa | 2:1 (end) | | | Konyaspor – Trabzonspor | 2:2 (end) | | | Başakşehir – Ankaragücü | 2:1 (end) |
| Yeni Malatyaspor – BB Erzurumspor | 3:1 (end) |
final
Liverpool FC
2:0
(1:0)
Wolverhampton Wanderers
Goals:
17. Mané, 81. Mané (Alexander-Arnold)
Ball possession: 59 % : 41 %.
Shots on target: 5:2. Shots off target: 8:5. Corners: 4:1. Offsides: 3:1. Fouls: 3:11.
Referees: M. Atkinson
Attendance:
Cards: 49. R. Bennett (WOS), 50. Diogo Jota (WOS)
Penalty missed:
Ball possession: 59 % : 41 %.
Shots on target: 5:2. Shots off target: 8:5. Corners: 4:1. Offsides: 3:1. Fouls: 3:11.
Liverpool FC:
Alisson – Alexander-Arnold, Matip, V. van Dijk, Robertson (84. Joe Gomez) – Хендерсон (C), Fabinho, Wijnaldum (88. Oxlade-Chamberlain) – M. Salah, Origi (64. Milner), Mané.
Subs: Mignolet – Lovren, Joe Gomez, Milner, Oxlade-Chamberlain, Shaqiri, Sturridge.
Coach:
Wolverhampton Wanderers: Patrício – R. Bennett, Coady (C), Boly – Doherty (80. Traoré), Dendoncker, Neves, Moutinho (84. Gibbs-White), J. Castro (84. Vinagre) – Jiménez, Diogo Jota.
Subs: Ruddy – Vinagre, Kilman, Gibbs-White, Cavaleiro, Costa, Traoré.
Coach:
Subs: Mignolet – Lovren, Joe Gomez, Milner, Oxlade-Chamberlain, Shaqiri, Sturridge.
Coach:
Wolverhampton Wanderers: Patrício – R. Bennett, Coady (C), Boly – Doherty (80. Traoré), Dendoncker, Neves, Moutinho (84. Gibbs-White), J. Castro (84. Vinagre) – Jiménez, Diogo Jota.
Subs: Ruddy – Vinagre, Kilman, Gibbs-White, Cavaleiro, Costa, Traoré.
Coach:
Referees: M. Atkinson
Attendance:
Liverpool FC substitution: Andrew Robertson is replaced by Joe Gomez.