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| Sheffield Utd. – Crystal Palace | 1:0 (end) | | | Chelsea – Leicester | 1:1 (end) |
| Alavés – Levante | 1:0 (end) | | | Espanyol – Sevilla | 0:2 (end) | | | Betis – Valladolid | 1:2 (end) |
| Atlético – Getafe | 1:0 (end) |
| Frankfurt – Hoffenheim | 1:0 (end) | | | Union Berlín – RB Leipzig | 0:4 (end) |
| Sittard – Willem II | 2:3 (end) | | | Twente – Waalwijk | 3:3 (end) | | | Feyenoord – Utrecht | 1:1 (end) |
| Alkmaar – Groningen | 0:0 (end) | | | Heracles – Eindhoven | 0:2 (end) |
| Standard – Mouscron | 4:1 (end) | | | Antwerp – Sint-Truiden | 2:0 (end) | | | Gent – Oostende | 2:0 (end) |
| Porto – Setúbal | 4:0 (end) | | | Aves – Marítimo | 3:1 (end) | | | FC Ferreira – Santa Clara | 0:1 (end) |
| Guimarães – Boavista | 1:1 (end) | | | Sporting – Braga | 2:1 (end) |
| Rheindorf Altach – Hartberg | 3:3 (end) | | | Austria – Admira | 1:1 (end) | | | Sturm Graz – Rapid | 0:1 (end) |
| Kazaň – Arsenal Tula | 1:0 (end) | | | Ufa – Rostov | 2:0 (end) | | | Dynamo – Lok. Moskva | 1:2 (end) |
| Sparta – Ostrava | 2:0 (end) | | | Karviná – Liberec | 0:1 (end) | | | Jablonec – Mladá Boleslav | 2:1 (end) |
| Teplice – Plzeň | 1:1 (end) |
| Dunajská Streda – Michalovce | 1:1 (end) |
| Konyaspor – Ankaragücü | 0:0 (end) | | | Göztepe – Antalyaspor | 0:1 (end) | | | Kasımpaşa – Trabzonspor | 1:1 (end) |
| Yeni Malatyaspor – Başakşehir | 3:0 (end) |
final
Espanyol Barcelona
0:2
(0:1)
Sevilla FC
Goals:
44. Reguilón, 87. Nolito (Reguilón)
Ball possession: 44 % : 56 %.
Shots on target: 2:4. Shots off target: 2:6. Corners: 8:4. Offsides: 2:4. Fouls: 11:17.
Referees: Martínez – Prieto, Noval
Attendance:
Cards: 53. V. Sánchez (ESB), 59. Vargas (ESB) – 40. Reguilón (SEV), 50. Ocampos (SEV)
Penalty missed:
Ball possession: 44 % : 56 %.
Shots on target: 2:4. Shots off target: 2:6. Corners: 8:4. Offsides: 2:4. Fouls: 11:17.
Espanyol Barcelona:
Diego López – Javi López, Naldo, Lluis López, Vilà – Melendo, Roca, V. Sánchez (66. Darder), Vargas – Ferreyra (82. F. Calero), Lej (72. Puado).
Subs: Prieto – Iturraspe, F. Calero, Darder, Granero, Campuzano, Puado.
Coach:
Sevilla FC: Vaclík – Navas, Diego Carlos (76. Koundé), Carriço, Reguilón – Jordán, Fernando, Ó. Torres (77. Gudelj) – Ocampos (62. Munir), L. de Jong, Nolito.
Subs: S. Rico – Munir, Koundé, Escudero, Gudelj, F. Vázquez, Gil.
Coach:
Subs: Prieto – Iturraspe, F. Calero, Darder, Granero, Campuzano, Puado.
Coach:
Sevilla FC: Vaclík – Navas, Diego Carlos (76. Koundé), Carriço, Reguilón – Jordán, Fernando, Ó. Torres (77. Gudelj) – Ocampos (62. Munir), L. de Jong, Nolito.
Subs: S. Rico – Munir, Koundé, Escudero, Gudelj, F. Vázquez, Gil.
Coach:
Referees: Martínez – Prieto, Noval
Attendance:
Scorer is NOLITO. Assisted by Sergio Reguilón.
Scorer is SERGIO REGUILÓN.