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| Helsinki – Maribor | 1:0 (end) | | | Slovácko – Fenerbahce | 1:1 (end) | | | Dudelange – Malmö | 2:2 (end) |
| Slovan Bratislava – Olympiacos | 2:2 (3:4 after SO) | | | Partizan Bělehrad – Larnaca | 2:2 (end) |
| Kyzylzhar – APOEL | 0:0 (end) | | | Tobol Kostanaj – Zrinjski Mostar | 1:1 (end) | | | Kluž – Soligorsk | 1:0 (end) |
| Twente – Čukarički | 4:1 (end) | | | Konyaspor – Vaduz | 2:4 (end) | | | Djurgården – Sepsi | 3:1 (end) |
| CS Petrocub – Fehérvár | 1:2 (end) | | | Basel – Brøndby | 2:1 (3:1 after SO) | | | Be'er Sheva – Lugano | 3:1 (end) |
| Antwerp – Lillestrøm | 2:0 (end) | | | FCSB – Dunajská Streda | 1:0 (end) | | | Universitatea Craiova – Zorja Luhansk | 3:0 (end) |
| Panathinaikos – Slavia | 1:1 (end) | | | Hibernians – RFS Riga | 1:3 (end) | | | KÍ Klaksvík – FC Ballkani | 2:1 (3:4 after SO) |
| Shkëndija – AIK Stockholm | 1:1 (2:3 after SO) | | | Anderlecht – Paide | 3:0 (end) | | | Aris Soluň – Maccabi Tel Aviv | 2:1 (end) |
| Levski – Hamrun | 1:2 (1:4 after SO) | | | Rapid – Neftçi Baku | 2:0 (after OT) | | | Başakşehir – Breidablik | 3:0 (end) |
| St Patrick´s – CSKA Sofia | 0:2 (end) | | | Young Boys – KuPS | 3:0 (end) | | | Kisvárda FC – Molde | 2:1 (end) |
final
FK Partizan Bělehrad 
2:2
(1:0)
AEK Larnaca |
90+2
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Yellow card for team AEK Larnaca FC ().
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90+1
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Yellow card for team AEK Larnaca FC (Rafail Mamas).
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81
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Yellow card for team AEK Larnaca FC (Ismael Casado).
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62
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Yellow card for team FK Partizan Bělehrad (Slobodan Urošević).
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60
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Yellow card for team FK Partizan Bělehrad (Svetozar Marković).
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52
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Yellow card for team FK Partizan Bělehrad (Bibras Natcho).
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Goals:
24. Gomes, 54. Gomes – 51. Lopes, 57. Faraj
Ball possession: 48 % : 52 %.
Shots on target: 6:3. Shots off target: 2:3. Corners: 4:3. Offsides: 6:0. Fouls: 19:12.
Referees: J. M. Sanches
Attendance:
Cards: 52. Natcho (PAB), 60. Marković (PAB), 62. Urošević (PAB) – 81. Casado (LAR), 90+1. Mamas (LAR)
Penalty missed:
Ball possession: 48 % : 52 %.
Shots on target: 6:3. Shots off target: 2:3. Corners: 4:3. Offsides: 6:0. Fouls: 19:12.
FK Partizan Bělehrad:
Popović – Urosević, Markovič, Vujacic, Filipović – Andrade, Fejsa – Menig, Natcho, Diabate – Gomes
Subs: Baždar, Belić, Ilić, Jović, Lukač (B), Lutovac, Petković, Sanicanin, Stevanović (B), Šehović, Terzić, Živković
Coach: I. Stolica
AEK Larnaca: Pirič – Rosales, Miličević, Tomović, Englezou – Oier, Gustavo, Faraj, Altman, Gyurcso – Rafa Lopes
Subs: Andreou, Casado, Gama, Gonzalez, Mamas, Maoum, Olatunji, Romo, Stylianidis (B), Toumpas (B), Trickovski
Coach: J. Oltra
Subs: Baždar, Belić, Ilić, Jović, Lukač (B), Lutovac, Petković, Sanicanin, Stevanović (B), Šehović, Terzić, Živković
Coach: I. Stolica
AEK Larnaca: Pirič – Rosales, Miličević, Tomović, Englezou – Oier, Gustavo, Faraj, Altman, Gyurcso – Rafa Lopes
Subs: Andreou, Casado, Gama, Gonzalez, Mamas, Maoum, Olatunji, Romo, Stylianidis (B), Toumpas (B), Trickovski
Coach: J. Oltra
Referees: J. M. Sanches
Attendance:
04.08.2022
Larnaca - Partizan Bělehrad 2:1
Shots on target: 5:6. Shots off target: 1:6. Corners: 8:3. Offsides: 3:3. Fouls: 9:14.
Larnaca - Partizan Bělehrad 2:1
Goals: 34. Garcia, 70. Miličević – 18. Menig
Cards: 59. Oier (LAR), 68. Tomović (LAR) – 59. Vujačić (PAB), 59. Urošević (PAB), 83. Fejsa (PAB), 90+3. Belić (PAB)
Ball possession: 51 % : 49 %.Shots on target: 5:6. Shots off target: 1:6. Corners: 8:3. Offsides: 3:3. Fouls: 9:14.