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All times are CEST (UTC + 2)
| Bournemouth – Brighton | 0:0 (post.) | | | Leicester – Aston Villa | 0:0 (post.) | | | Liverpool – Wolverhampton | 0:0 (post.) |
| Manchester City – Tottenham | 0:0 (post.) |
| Rayo Vallecano – Valencia | 2:1 (end) | | | Espanyol – Sevilla | 2:3 (end) | | | Cadiz – Barcelona | 0:4 (end) |
| Atlético – Celta Vigo | 4:1 (end) |
| Bayern – Stuttgart | 2:2 (end) | | | Frankfurt – Wolfsburg | 0:1 (end) | | | Hertha – Leverkusen | 2:2 (end) |
| Hoffenheim – Mohuč | 4:1 (end) | | | RB Leipzig – Dortmund | 3:0 (end) | | | Schalke – Bochum | 3:1 (end) |
| Zlín – Brno | 2:3 (end) | | | Olomouc – Plzeň | 2:3 (end) | | | Teplice – Sparta | 2:2 (end) |
| Skalica – Dunajská Streda | 1:1 (end) | | | Michalovce – Podbrezová | 0:0 (post.) |
| Rijeka – Osijek | 0:3 (end) | | | Gorica – Dinamo Zagreb | 0:1 (end) |
postponed
Leicester City
0:0
(-:-)
Aston Villa FC
Goals:
Referees:
Attendance:
Penalty missed:
Leicester City:
Subs:
Coach:
Aston Villa FC:
Subs:
Coach:
Subs:
Coach:
Aston Villa FC:
Subs:
Coach:
Referees:
Attendance:
Álex Moreno is replaced by Lucas Digne,
Ashley Young is replaced by Calum Chambers,
Leon Bailey is replaced by Bertrand Traoré.
James Maddison is replaced by Ricardo Pereira.
Jacob Ramsey is replaced by Jhon Durán.
Jamie Vardy is replaced by Patson Daka.