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| Astana – Plzeň | 1:2 (end) | | | Beşiktaş – Lugano | 2:3 (end) | | | Bodö/Glimt – Club Bruggy | 0:1 (end) |
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| KÍ Klaksvík – Lille | 0:0 (end) | | | Ljubljana – Slovan Bratislava | 0:1 (end) | | | Aberdeen – Helsinki | 1:1 (end) |
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| Fiorentina – Ferencváros | 2:2 (end) | | | Nordsjaelland – Ludogorec | 7:1 (end) | | | PAOK – Frankfurt | 2:1 (end) |
| Trnava – Fenerbahce | 1:2 (end) |
| AEK Atény – Ajax | 1:1 (end) | | | Aris Limassol – Rangers | 2:1 (end) | | | Betis – Sparta | 2:1 (end) |
| Freiburg – West Ham | 1:2 (end) | | | Marseille – Brighton | 2:2 (end) | | | Raków – Sturm Graz | 0:1 (end) |
| Sporting – Atalanta BC | 1:2 (end) | | | Bačka Topola – Olympiacos | 2:2 (end) | | | Roma – Servette FC | 4:0 (end) |
| Häcken – Qarabağ FK | 0:1 (end) | | | Liverpool – St.Gilloise | 2:0 (end) | | | Maccabi Haifa – Panathinaikos | 0:0 (end) |
| Molde – Leverkusen | 1:2 (end) | | | Slavia – FC Sheriff | 6:0 (end) | | | Toulouse – Linz | 1:0 (end) |
| Villarreal – Rennes | 1:0 (end) |
final
SC Freiburg 
1:2
(0:1)
West Ham United |
48
|
Yellow card for team West Ham United (Edson Álvarez).
|
|
|
25
|
Yellow card for team SC Freiburg (Nicolas Höfler).
|
Goals:
49. Sallai – 9. Paquetá (Bowen), 66. Aguerd (Ward-Prowse)
Ball possession: 55 % : 45 %.
Shots on target: 5:5. Shots off target: 4:4. Corners: 3:4. Offsides: 0:2. Fouls: 8:6.
Referees: Al Hakim – Klyver, Vilde
Attendance:
Cards: 25. Höfler (FRE) – 48. Álvarez (WHU)
Penalty missed:
Ball possession: 55 % : 45 %.
Shots on target: 5:5. Shots off target: 4:4. Corners: 3:4. Offsides: 0:2. Fouls: 8:6.
SC Freiburg:
Atubolu – Sildillia, Ginter, Lienhart – Sallai, Eggestein (76. Röhl), Höfler, Kübler (76. Weißhaupt) – Adamu (46. Doan), Höler (76. Philipp), Grifo (C) (86. Breunig).
Subs: Müller, Uphoff – Gulde, Makengo, K. Schmidt, Rüdlin.
Coach: C. Streich
West Ham United: Fabiański (C) – Coufal, Mavropanos, Álvarez, Kehrer (71. Palmieri), Aguerd – Ward-Prowse (90. Ings), Paquetá, Fornals (71. Souček) – Bowen, Kudus (80. Benrahma).
Subs: Anang, Aréola – Cornet, Coventry, Mubama, Ogbonna, Zouma.
Coach: D. Moyes
Subs: Müller, Uphoff – Gulde, Makengo, K. Schmidt, Rüdlin.
Coach: C. Streich
West Ham United: Fabiański (C) – Coufal, Mavropanos, Álvarez, Kehrer (71. Palmieri), Aguerd – Ward-Prowse (90. Ings), Paquetá, Fornals (71. Souček) – Bowen, Kudus (80. Benrahma).
Subs: Anang, Aréola – Cornet, Coventry, Mubama, Ogbonna, Zouma.
Coach: D. Moyes
Referees: Al Hakim – Klyver, Vilde
Attendance: