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| Astana – Plzeň | 1:2 (end) | | | Beşiktaş – Lugano | 2:3 (end) | | | Bodö/Glimt – Club Bruggy | 0:1 (end) |
| Breidablik – Zorja Luhansk | 0:1 (end) | | | FC Ballkani – Dinamo Zagreb | 2:0 (end) | | | Gent – Maccabi Tel Aviv | 2:0 (end) |
| KÍ Klaksvík – Lille | 0:0 (end) | | | Ljubljana – Slovan Bratislava | 0:1 (end) | | | Aberdeen – Helsinki | 1:1 (end) |
| Alkmaar – Legia | 1:0 (end) | | | Aston Villa – Zrinjski Mostar | 1:0 (end) | | | Čukarički – Genk | 0:2 (end) |
| Fiorentina – Ferencváros | 2:2 (end) | | | Nordsjaelland – Ludogorec | 7:1 (end) | | | PAOK – Frankfurt | 2:1 (end) |
| Trnava – Fenerbahce | 1:2 (end) |
| AEK Atény – Ajax | 1:1 (end) | | | Aris Limassol – Rangers | 2:1 (end) | | | Betis – Sparta | 2:1 (end) |
| Freiburg – West Ham | 1:2 (end) | | | Marseille – Brighton | 2:2 (end) | | | Raków – Sturm Graz | 0:1 (end) |
| Sporting – Atalanta BC | 1:2 (end) | | | Bačka Topola – Olympiacos | 2:2 (end) | | | Roma – Servette FC | 4:0 (end) |
| Häcken – Qarabağ FK | 0:1 (end) | | | Liverpool – St.Gilloise | 2:0 (end) | | | Maccabi Haifa – Panathinaikos | 0:0 (end) |
| Molde – Leverkusen | 1:2 (end) | | | Slavia – FC Sheriff | 6:0 (end) | | | Toulouse – Linz | 1:0 (end) |
| Villarreal – Rennes | 1:0 (end) |
final
Villarreal CF 
1:0
(1:0)
Stade Rennes |
59
|
Yellow card for team Stade Rennes FC (Adrien Truffert).
|
|
|
54
|
Yellow card for team Villarreal CF (Alejandro Baena).
|
|
|
50
|
Yellow card for team Villarreal CF (Alberto Moreno).
|
|
|
43
|
Yellow card for team Villarreal CF (Yeremi Pino).
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|
|
27
|
Yellow card for team Stade Rennes FC (Désiré Doué).
|
Goals:
36. Sörloth (Pino)
Ball possession: 47 % : 53 %.
Shots on target: 2:3. Shots off target: 3:8. Corners: 3:6. Offsides: 3:1. Fouls: 15:18.
Referees: Lechner – Heidenreich, Kolbitsch (AUT)
Attendance:
Cards: 43. Pino (VLR), 50. A. Moreno (VLR), 54. Baena (VLR) – 27. D. Doué (REN), 59. Truffert (REN)
Penalty missed: 90+2. Terrier (REN), keeper Reina saved
Ball possession: 47 % : 53 %.
Shots on target: 2:3. Shots off target: 3:8. Corners: 3:6. Offsides: 3:1. Fouls: 15:18.
Villarreal CF:
Reina – Femenía, Mándí, Gabbia, A. Moreno (85. Albiol) – Capoue, Parejo – Baena (57. Pedraza), Trigueros (C) (74. Comesaña), Pino (57. Morales) – Sörloth (85. Terrats).
Subs: Jörgensen – Cuenca, Brereton Díaz, Altimira, Akhomach.
Coach: José Rojo Martin
Stade Rennes: Mandanda – G. Doué, Omari, Theate, Truffert – Bourigeaud (C) (73. Le Fée), Santamaría (73. Matić), D. Doué (81. Terrier) – Blas, Yıldırım (64. Kalimuendo), Salah (64. Gouiri).
Subs: Gallon, Lembet – Wooh, Belocian, Assignon, Rieder, Jaouab.
Coach: Bruno Génésio
Subs: Jörgensen – Cuenca, Brereton Díaz, Altimira, Akhomach.
Coach: José Rojo Martin
Stade Rennes: Mandanda – G. Doué, Omari, Theate, Truffert – Bourigeaud (C) (73. Le Fée), Santamaría (73. Matić), D. Doué (81. Terrier) – Blas, Yıldırım (64. Kalimuendo), Salah (64. Gouiri).
Subs: Gallon, Lembet – Wooh, Belocian, Assignon, Rieder, Jaouab.
Coach: Bruno Génésio
Referees: Lechner – Heidenreich, Kolbitsch (AUT)
Attendance: