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| Tottenham – Huddersfield Town | 4:0 (end) | | | Southampton – Wolverhampton | 3:1 (end) | | | Man Utd. – West Ham | 2:1 (end) |
| Espanyol – Alavés | 2:1 (end) | | | Huesca – Barcelona | 0:0 (end) | | | Atlético – Celta Vigo | 2:0 (end) |
| Sevilla – Betis | 3:2 (end) |
| Bremen – Freiburg | 2:1 (end) | | | Hannover – Mönchengladbach | 0:1 (end) | | | RB Leipzig – Wolfsburg | 2:0 (end) |
| Stuttgart – Leverkusen | 0:1 (end) | | | Dortmund – Mohuč | 2:1 (end) |
| Alkmaar – Den Haag | 2:3 (end) | | | Ajax – Excelsior | 6:2 (end) | | | Feyenoord – Heracles | 2:1 (end) |
| Sittard – Venlo | 1:1 (end) |
| Beerschot – Eupen | 2:0 (end) | | | Waregem – Mouscron | 2:2 (end) | | | Kortrijk – St.Gilloise | 0:1 (end) |
| Sint-Truiden – Oostende | 1:0 (end) | | | Gent – Antwerp | 1:2 (end) |
| Santa Clara – Moreirense | 1:1 (end) | | | Portimonense – Porto | 0:3 (end) | | | Aves – Sporting | 1:3 (end) |
| Hartberg – Rheindorf Altach | 0:1 (end) | | | Wacker – Admira | 1:3 (end) | | | Rapid – Mattersburg | 2:1 (end) |
| Jenisej – Ufa | 0:0 (end) | | | Arsenal Tula – Ural | 0:0 (end) | | | CSKA Moskva – Orenburg | 2:3 (end) |
| Grozny – Lok. Moskva | 1:3 (end) |
| Slovácko – Příbram | 2:0 (end) | | | Opava – Olomouc | 2:1 (end) | | | Karviná – Zlín | 2:0 (end) |
| Plzeň – Ostrava | 2:1 (end) |
| Sereď – Dunajská Streda | 0:5 (end) | | | Ružomberok – Michalovce | 1:0 (end) | | | Trenčín – Zlaté Moravce | 1:0 (end) |
| Senica – Nitra | 4:1 (end) | | | Podbrezová – Trnava | 0:0 (end) |
| Rizespor – Göztepe | 1:0 (end) | | | Konyaspor – Sivasspor | 1:1 (end) | | | Beşiktaş – Başakşehir | 2:1 (end) |
final
VfB Stuttgart
0:1
(0:0)
Bayer 04 Leverkusen
Goals:
64. Havertz (pen.)
Ball possession: 30 % : 70 %.
Shots on target: 5:5. Shots off target: 4:8. Corners: 4:6. Offsides: 5:1. Fouls: 15:10.
Referees: Stieler – Jöllenbeck, Gittelmann
Attendance: 53 657
Cards: 43. Beck (STU) 90+1. Ascacibar (STU)
Penalty missed:
Ball possession: 30 % : 70 %.
Shots on target: 5:5. Shots off target: 4:8. Corners: 4:6. Offsides: 5:1. Fouls: 15:10.
VfB Stuttgart:
Zieler – Kabak, Pavard, Kempf – Beck (C), Esswein, G. Castro, Ascacibar, Zuber (82. Mario Gómez) – Didavi (68. Thommy), N. González (70. Donis).
Subs: Grahl – Sosa, Emiliano Insúa, Baumgartl, Thommy, Donis, Mario Gómez.
Coach:
Bayer 04 Leverkusen: Hrádecký – Weiser, Tah, S. Bender, Wendell – Aránguiz, Baumgartlinger, Brandt – Havertz, Volland (C), Bailey (78. Alario).
Subs: R. Özcan – Jedvaj, Dragović, Paulinho, Kohr, Alario, Thelin.
Coach:
Subs: Grahl – Sosa, Emiliano Insúa, Baumgartl, Thommy, Donis, Mario Gómez.
Coach:
Bayer 04 Leverkusen: Hrádecký – Weiser, Tah, S. Bender, Wendell – Aránguiz, Baumgartlinger, Brandt – Havertz, Volland (C), Bailey (78. Alario).
Subs: R. Özcan – Jedvaj, Dragović, Paulinho, Kohr, Alario, Thelin.
Coach:
Referees: Stieler – Jöllenbeck, Gittelmann
Attendance: 53 657
Scorer from a penalty shot is KAI HAVERTZ..