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| Man Utd. – Manchester City | 1:2 (end) | | | Bournemouth – West Brom | 1:0 (end) | | | Arsenal – Southampton | 2:1 (end) |
| Burnley – Hull City | 1:1 (end) | | | Middlesbrough – Crystal Palace | 1:2 (end) | | | Stoke – Tottenham | 0:4 (end) |
| West Ham – Watford | 2:4 (end) | | | Liverpool – Leicester | 4:1 (end) |
| Celta Vigo – Atlético | 0:4 (end) | | | Real – Osasuna | 5:2 (end) | | | Malaga – Villarreal | 0:2 (end) |
| Sevilla – Las Palmas | 2:1 (end) | | | Barcelona – Alavés | 1:2 (end) |
| Leverkusen – Hamburg | 3:1 (end) | | | Wolfsburg – Kolín nad Rýnem | 0:0 (end) | | | Ingolstadt – Hertha | 0:2 (end) |
| Darmstadt – Frankfurt | 1:0 (end) | | | Freiburg – Mönchengladbach | 3:1 (end) | | | RB Leipzig – Dortmund | 1:0 (end) |
| Alkmaar – Willem II | 2:0 (end) | | | Zwolle – Utrecht | 1:1 (end) | | | Nijmegen – Eindhoven | 0:4 (end) |
| Heerenveen – Twente | 3:1 (end) | | | Excelsior – Heracles | 3:1 (end) |
| Eupen – Oostende | 2:1 (end) | | | Kortrijk – Westerlo | 4:1 (end) | | | Mechelen – Sint-Truiden | 2:0 (end) |
| Mouscron – Waregem | 1:5 (end) |
| Belenenses – Nacional | 2:1 (end) | | | Sporting – Moreirense | 3:0 (end) | | | Porto – Guimarães | 3:0 (end) |
| Sturm Graz – Rapid | 1:1 (end) | | | Austria – Wolfsberger | 4:1 (end) | | | Rheindorf Altach – Mattersburg | 2:1 (end) |
| St. Pölten – Ried | 2:3 (end) |
| Perm – Tomsk | 1:0 (end) | | | Orenburg – Machačkala | 0:0 (end) | | | CSKA Moskva – Grozny | 3:0 (end) |
| Sparta – Mladá Boleslav | 2:2 (end) | | | Hradec Králové – Příbram | 2:0 (end) | | | Karviná – Jihlava | 3:0 (end) |
| Liberec – Plzeň | 1:2 (end) |
| Trenčín – Trnava | 3:3 (end) | | | Slovan Bratislava – Myjava | 1:2 (end) | | | Michalovce – Žilina | 0:2 (end) |
| Senica – Ružomberok | 1:1 (end) |
Goals:
89. Sarabia (pen.), 90+4. Fernández Luna – 16. Tana
Ball possession: 65 % : 35 %.
Shots on target: 7:4. Shots off target: 6:1. Corners: 10:1. Offsides: 5:4. Fouls: 15:13.
Referees: Juan Martínez – Roberto Alonso, César Noval
Attendance:
Cards: 9. F. Vázquez (SEV), 54. Pareja (SEV), 81. Mariano (SEV) – 45. Livaja (LPA), 54. Mesa (LPA), 57. Bigas (LPA), 81. Araujo (LPA), 90+4. Momo (LPA) 88. Bigas (LPA)
Penalty missed:
Ball possession: 65 % : 35 %.
Shots on target: 7:4. Shots off target: 6:1. Corners: 10:1. Offsides: 5:4. Fouls: 15:13.
Sevilla FC:
S. Rico – Mariano, Rami, Pareja, Escudero – F. Vázquez, N'Zonzi, Ganso (46. Vitolo) – Correa (67. Sarabia), Ben Yedder (66. Fernández Luna), Nasri.
Subs: Sirigu – Fernández Luna, Iborra, Vitolo, Sarabia, Mercado, Kolodziejczak.
Coach:
UD Las Palmas: Varas – Michel, David García, Bigas, D. Castellano – V. Gómez (79. Montoro), Mesa, Tana (76. Araujo) – Mateo (56. Momo), Livaja, El Zhar.
Subs: Lizoain – Lemos, Araujo, Simón, Tyronne, Montoro, Momo.
Coach:
Subs: Sirigu – Fernández Luna, Iborra, Vitolo, Sarabia, Mercado, Kolodziejczak.
Coach:
UD Las Palmas: Varas – Michel, David García, Bigas, D. Castellano – V. Gómez (79. Montoro), Mesa, Tana (76. Araujo) – Mateo (56. Momo), Livaja, El Zhar.
Subs: Lizoain – Lemos, Araujo, Simón, Tyronne, Montoro, Momo.
Coach:
Referees: Juan Martínez – Roberto Alonso, César Noval
Attendance:
Nicolás Pareja (Sevilla FC) is shown a yellow card.