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All times are CEST (UTC + 2)
| Chelsea – Man Utd. | 2:2 (end) | | | Bournemouth – Southampton | 0:0 (end) | | | Manchester City – Burnley | 5:0 (end) |
| West Ham – Tottenham | 0:1 (end) | | | Wolverhampton – Watford | 0:2 (end) | | | Huddersfield Town – Liverpool | 0:1 (end) |
| Real – Levante | 1:2 (end) | | | Valencia – Leganés | 1:1 (end) | | | Villarreal – Atlético | 1:1 (end) |
| Barcelona – Sevilla | 4:2 (end) |
| Augsburg – RB Leipzig | 0:0 (end) | | | Leverkusen – Hannover | 2:2 (end) | | | Norimberk – Hoffenheim | 1:3 (end) |
| Stuttgart – Dortmund | 0:4 (end) | | | Wolfsburg – Bayern | 1:3 (end) | | | Schalke – Bremen | 0:2 (end) |
| Excelsior – Arnhem | 2:0 (end) | | | Eindhoven – Emmen | 6:0 (end) | | | Heerenveen – Ajax | 0:4 (end) |
| Utrecht – Alkmaar | 2:1 (end) |
| Mouscron – Standard | 0:0 (end) | | | Antwerp – Lokeren | 2:1 (end) | | | Kortrijk – Sint-Truiden | 3:1 (end) |
| Genk – Eupen | 2:1 (end) |
| Hartberg – Rapid | 3:0 (end) | | | Linz – Rheindorf Altach | 1:1 (end) | | | Salzburg – Wacker | 1:1 (end) |
| Orenburg – Jenisej | 0:0 (end) | | | Ural – Samara | 1:1 (end) | | | Ufa – Kazaň | 0:0 (end) |
| Olomouc – Zlín | 1:1 (end) | | | Příbram – Jablonec | 0:6 (end) | | | Ostrava – Karviná | 1:1 (end) |
| Slovácko – Teplice | 0:2 (end) |
| Trnava – Senica | 4:1 (end) | | | Slovan Bratislava – Zlaté Moravce | 3:1 (end) | | | Dunajská Streda – Podbrezová | 3:2 (end) |
| Žilina – Michalovce | 2:2 (end) |
final
AFC Bournemouth
0:0
(0:0)
Southampton FC
Goals:
Ball possession: 58 % : 42 %.
Shots on target: 2:4. Shots off target: 6:2. Corners: 6:4. Offsides: 1:4. Fouls: 10:14.
Referees: Lee Probert – Simon Beck, Andy Garratt.
Attendance:
Cards: 86. C. Wilson (BTH) – 33. Bertrand (SOT), 41. Lemina (SOT)
Penalty missed:
Ball possession: 58 % : 42 %.
Shots on target: 2:4. Shots off target: 6:2. Corners: 6:4. Offsides: 1:4. Fouls: 10:14.
AFC Bournemouth:
Begović – Francis, S. Cook, Aké, A. Smith – Lerma, L. Cook, Brooks (59. Stanislas), Fraser (76. Ibe) – C. Wilson, J. King (85. Gosling).
Subs: Boruc – Rico, Gosling, Surman, Ibe, Stanislas, Defoe.
Coach:
Southampton FC: A. McCarthy – Soares, Stephens, Hoedt, Bertrand – M. Elyounoussi, Lemina (66. Armstrong), Redmond, P.-E. Höjbjerg – Ings (77. Gabbiadini), Ch. Austin (77. S. Long).
Subs: Gunn – Jošida, Vestergaard, Ward-Prowse, Armstrong, S. Long, Gabbiadini.
Coach:
Subs: Boruc – Rico, Gosling, Surman, Ibe, Stanislas, Defoe.
Coach:
Southampton FC: A. McCarthy – Soares, Stephens, Hoedt, Bertrand – M. Elyounoussi, Lemina (66. Armstrong), Redmond, P.-E. Höjbjerg – Ings (77. Gabbiadini), Ch. Austin (77. S. Long).
Subs: Gunn – Jošida, Vestergaard, Ward-Prowse, Armstrong, S. Long, Gabbiadini.
Coach:
Referees: Lee Probert – Simon Beck, Andy Garratt.
Attendance:
Southampton FC substitution: Danny Ings is replaced by Manolo Gabbiadini.